Altered Theta Oscillations and Aberrant Cortical Excitatory Activity in the 5XFAD Model of Alzheimer’s Disease

Figure 7

Percentage change in theta duration during light/dark switch. Data from Figures 6(b), 6(c), 6(e), and 6(f) were used to calculate the percentage change in theta duration for every individual mouse during the total observation period (48 h, (a)), during nonmotor activity (b) and motor activity (not shown). During switch from light to dark cycle a statistic trend for theta duration increase turned out to exist in 5XFAD mice (a). Again, this effect was most prominent and significant during no motor activity (b) and absent during motor activity.

(a)

(b)