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Neural Plasticity
Volume 2016, Article ID 1682972, 9 pages
http://dx.doi.org/10.1155/2016/1682972
Research Article

TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

1College of Basic Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210023, China
2College of Life Science, Nanjing Normal University, Nanjing 210046, China
3College of Basic Medicine, Guangxi University of Chinese Medicine, 13 Wuhe Road, Nanning 530200, China

Received 15 May 2015; Revised 31 August 2015; Accepted 3 September 2015

Academic Editor: Feng Wei

Copyright © 2016 Tunyu Jian et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Ikoma, M. Steinhoff, S. Ständer, G. Yosipovitch, and M. Schmelz, “The neurobiology of itch,” Nature Reviews Neuroscience, vol. 7, no. 7, pp. 535–547, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. D. M. Bautista, S. R. Wilson, and M. A. Hoon, “Why we scratch an itch: the molecules, cells and circuits of itch,” Nature Neuroscience, vol. 17, no. 2, pp. 175–182, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. S. R. Wilson, L. Thé, L. M. Batia et al., “The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch,” Cell, vol. 155, no. 2, pp. 285–295, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. W.-S. Shim, M.-H. Tak, M.-H. Lee et al., “TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase,” The Journal of Neuroscience, vol. 27, no. 9, pp. 2331–2337, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Nojima and E. Carstens, “5-hydroxytryptamine (5-HT)2 receptor involvement in acute 5-HT-evoked scratching but not in allergic pruritus induced by dinitrofluorobenzene in rats,” The Journal of Pharmacology and Experimental Therapeutics, vol. 306, no. 1, pp. 245–252, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. S. G. Shimada, K. A. Shimada, and J. G. Collins, “Scratching behavior in mice induced by the proteinase-activated receptor-2 agonist, SLIGRL-NH2,” European Journal of Pharmacology, vol. 530, no. 3, pp. 281–283, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Andoh, T. Nagasawa, M. Satoh, and Y. Kuraishi, “Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice,” The Journal of Pharmacology and Experimental Therapeutics, vol. 286, no. 3, pp. 1140–1145, 1998. View at Google Scholar · View at Scopus
  8. F. Cevikbas, X. Wang, T. Akiyama et al., “A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: involvement of TRPV1 and TRPA1,” The Journal of Allergy and Clinical Immunology, vol. 133, no. 2, pp. 448.e7–460.e7, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. W.-S. Shim and U. Oh, “Histamine-induced itch and its relationship with pain,” Molecular Pain, vol. 4, article no. 29, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Leurs, P. L. Chazot, F. C. Shenton, H. D. Lim, and I. J. P. De Esch, “Molecular and biochemical pharmacology of the histamine H4 receptor,” British Journal of Pharmacology, vol. 157, no. 1, pp. 14–23, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. J. K. Bell, D. S. McQueen, and J. L. Rees, “Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in BalbC mice,” British Journal of Pharmacology, vol. 142, no. 2, pp. 374–380, 2004. View at Publisher · View at Google Scholar · View at Scopus
  12. P. J. Dunford, K. N. Williams, P. J. Desai, L. Karlsson, D. McQueen, and R. L. Thurmond, “Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus,” The Journal of Allergy and Clinical Immunology, vol. 119, no. 1, pp. 176–183, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. J. M. Cowden, M. Zhang, P. J. Dunford, and R. L. Thurmond, “The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation,” Journal of Investigative Dermatology, vol. 130, no. 4, pp. 1023–1033, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Rossbach, C. Nassenstein, M. Gschwandtner et al., “Histamine H 1, H 3 and H 4 receptors are involved in pruritus,” Neuroscience, vol. 190, pp. 89–102, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. M. I. Strakhova, A. L. Nikkel, A. M. Manelli et al., “Localization of histamine H4 receptors in the central nervous system of human and rat,” Brain Research, vol. 1250, pp. 41–48, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Y. Kim, Z. Tang, Q. Liu et al., “Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1,” Cell, vol. 133, no. 3, pp. 475–485, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. Q. Liu, Z. Tang, L. Surdenikova et al., “Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus,” Cell, vol. 139, no. 7, pp. 1353–1365, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. M. S. Shapiro, L. P. Wollmuth, and B. Hille, “Modulation of Ca2+ channels by PTX-sensitive G-proteins is blocked by N-ethylmaleimide in rat sympathetic neurons,” The Journal of Neuroscience, vol. 14, no. 11, pp. 7109–7116, 1994. View at Google Scholar · View at Scopus
  19. M. Nakaya, N. Takeuchi, and K. Kondo, “Immunohistochemical localization of histamine receptor subtypes in human inferior turbinates,” The Annals of Otology, Rhinology, and Laryngology, vol. 113, no. 7, pp. 552–557, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. M. J. Marinissen and J. S. Gutkind, “G-protein-coupled receptors and signaling networks: emerging paradigms,” Trends in Pharmacological Sciences, vol. 22, no. 7, pp. 368–376, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. Q. Liu, P. Sikand, C. Ma et al., “Mechanisms of itch evoked by beta-alanine,” The Journal of Neuroscience, vol. 32, no. 42, pp. 14532–14537, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. R.-G. Zhuo, X.-Y. Ma, P.-L. Zhou et al., “Mas-related G protein-coupled receptor D is coupled to endogenous calcium-activated chloride channel in Xenopus oocytes,” Journal of Physiology and Biochemistry, vol. 70, no. 1, pp. 185–191, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. S.-K. Han, V. Mancino, and M. I. Simon, “Phospholipase Cβ 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons,” Neuron, vol. 52, no. 4, pp. 691–703, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. M. J. Caterina, M. A. Schumacher, M. Tominaga, T. A. Rosen, J. D. Levine, and D. Julius, “The capsaicin receptor: a heat-activated ion channel in the pain pathway,” Nature, vol. 389, no. 6653, pp. 816–824, 1997. View at Publisher · View at Google Scholar · View at Scopus
  25. B. M. Kim, S. H. Lee, W. S. Shim, and U. Oh, “Histamine-induced Ca2+ influx via the PLA2/lipoxygenase/TRPV1 pathway in rat sensory neurons,” Neuroscience Letters, vol. 361, no. 1–3, pp. 159–162, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. E. S. Fernandes, C. T. Vong, S. Quek et al., “Superoxide generation and leukocyte accumulation: key elements in the mediation of leukotriene B4-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1,” The FASEB Journal, vol. 27, no. 4, pp. 1664–1673, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. L. S. Premkumar and G. P. Ahern, “Induction of vanilloid receptor channel activity by protein kinase C,” Nature, vol. 408, no. 6815, pp. 985–990, 2000. View at Publisher · View at Google Scholar · View at Scopus
  28. G. P. Ahern, I. M. Brooks, R. L. Miyares, and X.-B. Wang, “Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling,” The Journal of Neuroscience, vol. 25, no. 21, pp. 5109–5116, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. D. H. Woo, S. J. Jung, M. H. Zhu et al., “Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG),” Molecular Pain, vol. 4, article 42, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. T. Rohacs, B. Thyagarajan, and V. Lukacs, “Phospholipase C mediated modulation of TRPV1 channels,” Molecular Neurobiology, vol. 37, no. 2-3, pp. 153–163, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. T. Bíró, B. I. Tóth, R. Marincsák, N. Dobrosi, T. Géczy, and R. Paus, “TRP channels as novel players in the pathogenesis and therapy of itch,” Biochimica et Biophysica Acta: Molecular Basis of Disease, vol. 1772, no. 8, pp. 1004–1021, 2007. View at Publisher · View at Google Scholar · View at Scopus
  32. T. Liu and R.-R. Ji, “New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?” Pflügers Archiv, vol. 465, no. 12, pp. 1671–1685, 2013. View at Publisher · View at Google Scholar
  33. F. E. R. Simons and K. J. Simons, “Histamine and H1-antihistamines: celebrating a century of progress,” The Journal of Allergy and Clinical Immunology, vol. 128, no. 6, pp. 1139–1150.e4, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. T. Akiyama and E. Carstens, “Neural processing of itch,” Neuroscience, vol. 250, pp. 697–71, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. S. Davidson and G. J. Giesler, “The multiple pathways for itch and their interactions with pain,” Trends in Neurosciences, vol. 33, no. 12, pp. 550–558, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. A. E. Kremer, J. Feramisco, P. W. Reeh, U. Beuers, and R. P. J. Oude Elferink, “Receptors, cells and circuits involved in pruritus of systemic disorders,” Biochimica et Biophysica Acta, vol. 1842, no. 7, pp. 869–892, 2014. View at Publisher · View at Google Scholar · View at Scopus