EEG Radiotelemetry in Small Laboratory Rodents: A Powerful State-of-the Art Approach in Neuropsychiatric, Neurodegenerative, and Epilepsy Research

Figure 1

Standard EEG radiotelemetry system and radiofrequency transmitters. Besides self-made systems, a number of commercially available systems are on the market. The basic setup of such system is depicted in (a). The system consists of a radiofrequency transmitter, the receiver plate, a data exchange matrix serving as a multiplexer, and the data acquisition, processing, and analysing core unit. For frequency analysis, seizure detection and sleep analysis specific software modules are offered. Multiple types of transmitters are available depending on which species is supposed to be investigated and depended on the scientific question. (b) Implanted mice, receiver plates, and a multiplexer placed inside a ventilated cabinet for standardized recording conditions. (c) An adult C57Bl/6J mouse and a 2-channel radiofrequency transmitter (TL11F20-EET; DSI). (d) Dorsal view of the skull 4 weeks after electrode implantation and fixation using glass ionomer cement. Figures 1(a) and 1(d) reprinted from [85], with permission from Elsevier.

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