Right Hemisphere Grey Matter Volume and Language Functions in Stroke Aphasia

Table 4

Results of VBM analyses by language measure.

Language Measure	Test	RH regions (AAL)	Cluster size	Peak coordinates			value	df	FWE correction	Benjamini-Hochberg correction	Effect size
				px	py	pz
Spoken word comprehension	NNB AC	Insula	1458	40.5	−4.5	−7.5	5.861	35	0.0000	0.0000	0.70
		MTG	732	55.5	−25.5	−4.5	4.646		0.0000	0.0001	0.62
Word semantic association	PALPA51			No sig. clusters
Sentence comprehension	NAVS SCT			No sig. clusters
Spoken word production	NNB CN	SMA	545	13.5	16.5	61.5	4.302	35	0.0001	0.0002	0.59
		Insula	267	40.5	−7.5	−7.5	4.106		0.0002	0.0003	0.57
Oral reading	PALPA35	SMA	502	13.5	15	61.5	4.549	34	0.0001	0.0001	0.62
		Pallidum	430	25.5	−1.5	−4.5	3.861		0.0005	0.0005	0.55
		Hippocampus	294	33	−28.5	−6	5.274		0.0000	0.0001	0.67
Spelling-to-dictation	PALPA40	Hippocampus	503	36	−1.5	−22.5	4.593	35	0.0001	0.0001	0.61
		Postcentral	258	49.5	−12	36	3.981		0.0003	0.0004	0.56
Sentence production	NAVS SPPT	SMA	275	13.5	15	58.5	4.625	34	0.0001	0.0001	0.62

Note. Table 4 summarizes regions where GM volume was significantly associated with language performance in both comprehension and production domains. The results are presented at a threshold of , based on voxel-level threshold and a minimum cluster size (665–708 mm³) determined by an estimate of image smoothness. In addition, cluster values were corrected for the total number of language measures examined () using the Benjamini-Hochberg procedure. Significant peak regions are reported with corresponding coordinates, T and values, degrees of freedom, and effect sizes; RH: right hemisphere; SMA: supplementary motor area; MTG: middle temporal gyrus.