Review Article

Rodent Models of Developmental Ischemic Stroke for Translational Research: Strengths and Weaknesses

Figure 2

(a) Molecular and environmental factors involved in physiological CST development in rodents. (b) Processes altered after a brain injury that hits during CST development. Insets show some of the mechanisms involved in the acute damage provoked by cerebral ischemia (excitotoxicity, top right) and the factor involved in the axonal pathfinding and midline crossing in the CST development (EphA4/EphrinB3, bottom right).
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