Neural Plasticity

Neural Plasticity after Congenital Brain Lesions


Status
Published

Lead Editor

1Stella Maris Infant Lab for Early Intervention and Infant Neurology Section, Pisa, Italy

2University of Pisa, Pisa, Italy

3University Children’s Hospital, Tübingen, Germany

4University of Queensland, Brisbane, Australia


Neural Plasticity after Congenital Brain Lesions

Description

Infants born with congenital brain lesions are at high risk of abnormal neurodevelopmental outcomes. Neuronal damage triggers complex processes of adaptive neuroplasticity, which involve various functional systems and are highly influenced by the environment. Understanding the complex process of reorganization of neural functions through adaptive plasticity is a fast-growing field of interest, as it may lead to more targeted and evidence-based interventions to promote neurodevelopment.

Congenital brain lesions present a compelling model for studying early brain plasticity. The potential of the neuroplastic mechanisms is thought to be stronger in the developing brain of children compared to adults. By means of noninvasive neuroimaging and electrophysiological techniques, as well as animal models, it is now possible to describe the specificity of early mechanisms of brain plasticity.

The goal of this special issue is to focus on early neuroplasticity following congenital brain lesions to identify specific mechanisms (including neural, molecular, or clinical signatures) and to identify novel targeted or synergetic early intervention strategies.

The topics may include reports of plasticity in all functions, including motor, language, visual, auditory, and somatosensory functions, and their possible interaction. All models of congenital brain injury will be considered, including global or focal injury.

Prospective and retrospective studies of neuroimaging and electrophysiological nature are especially welcome. Behavioral research submissions and review articles describing the current state of the art are also encouraged.

Potential topics include but are not limited to the following:

  • Contribution of any sensory or functional system to the clinical recovery after early injury
  • Evidence of early sensory-motor system neuroplasticity in neonates or infants
  • Plasticity in older individuals with congenital brain damage
  • Animal model brain plasticity research mimicking early brain injury
  • Spontaneous or treatment induced outcomes including (but not limited to) physical treatment, TMS, tDCS, and pharmacological or surgical interventions following early brain injury
  • Advanced techniques for the study of plasticity during early phases of brain development

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 9154282
  • - Editorial

Neural Plasticity after Congenital Brain Lesions

Simona Fiori | Martin Staudt | ... | Andrea Guzzetta
  • Special Issue
  • - Volume 2019
  • - Article ID 5089321
  • - Review Article

Rodent Models of Developmental Ischemic Stroke for Translational Research: Strengths and Weaknesses

Mariangela Gennaro | Alessandro Mattiello | Tommaso Pizzorusso
  • Special Issue
  • - Volume 2019
  • - Article ID 2184398
  • - Clinical Study

Transcranial Direct Current Stimulation (tDCS) in Unilateral Cerebral Palsy: A Pilot Study of Motor Effect

Emanuela Inguaggiato | Nadia Bolognini | ... | Giovanni Cioni
  • Special Issue
  • - Volume 2018
  • - Article ID 1435808
  • - Research Article

Impairments of Visuospatial Attention in Children with Unilateral Spastic Cerebral Palsy

Gaétan Ickx | Samar M. Hatem | ... | Yannick Bleyenheuft
  • Special Issue
  • - Volume 2018
  • - Article ID 8472807
  • - Research Article

Potentials of Ultrahigh-Field MRI for the Study of Somatosensory Reorganization in Congenital Hemiplegia

Simona Fiori | Laura Biagi | ... | Andrea Guzzetta
  • Special Issue
  • - Volume 2018
  • - Article ID 2831342
  • - Research Article

Time Course of Upper Limb Function in Children with Unilateral Cerebral Palsy: A Five-Year Follow-Up Study

Katrijn Klingels | Sarah Meyer | ... | Hilde Feys
  • Special Issue
  • - Volume 2018
  • - Article ID 9610812
  • - Clinical Study

Transcranial Direct Current Stimulation (tDCS) Paired with Occupation-Centered Bimanual Training in Children with Unilateral Cerebral Palsy: A Preliminary Study

Tonya L. Rich | Samuel Nemanich | ... | Bernadette T. Gillick
  • Special Issue
  • - Volume 2018
  • - Article ID 1265143
  • - Research Article

Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy

Svend Sparre Geertsen | Henrik Kirk | Jens Bo Nielsen
  • Special Issue
  • - Volume 2018
  • - Article ID 2671613
  • - Research Article

Corticospinal Tract Wiring and Brain Lesion Characteristics in Unilateral Cerebral Palsy: Determinants of Upper Limb Motor and Sensory Function

Cristina Simon-Martinez | Ellen Jaspers | ... | Hilde Feys
  • Special Issue
  • - Volume 2018
  • - Article ID 6950547
  • - Research Article

Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study

Giuseppina Sgandurra | Laura Biagi | ... | Giovanni Cioni
Neural Plasticity
 Journal metrics
Acceptance rate53%
Submission to final decision58 days
Acceptance to publication37 days
CiteScore6.900
Impact Factor3.093
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