Dosage Optimization for Letrozole Treatment in Clomiphene-Resistant Patients with Polycystic Ovary Syndrome: A Prospective Interventional Study

Table 3

Complication of letrozole in step-up protocol.

Dosage	AUB	Ovarian cyct
Letrozole 2.5 mg	2.08%	—
Letrozole 5 mg	2.63%	2.63%
Letrozole 7.5 mg	14.61%	3.7%

𝜒² for linear trend: 6.38, 𝑃<0.011.