Research Article
White Matter Damage in 4,725 Term-Born Infants Is Determined by Head Circumference at Birth: The Missing Link
Figure 2
Head circumference determines white matter damage (WMD) assessed by cranial ultrasound in 4,725 term-born neonates. A parabolic correlation curve was fitted to describe the relation between head circumference (HC) in centiles and the risk to develop white matter damage (%): WMD (%) = 3.1168–0.12797∗HC (centile) + 0.0014741∗HC2 (centile) (r = 0.957, ). Interestingly, from all growth variables at birth, only head circumference showed a close relation to the risk of white matter damage over the whole range of centiles (Table 2).