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Oxidative Medicine and Cellular Longevity
Volume 2012 (2012), Article ID 608478, 14 pages
http://dx.doi.org/10.1155/2012/608478
Review Article

ROS in Aging Caenorhabditis elegans: Damage or Signaling?

Laboratory for Aging Physiology and Molecular Evolution, Department of Biology, Ghent University, K. L. Ledeganckstraat 35, 9000 Ghent, Belgium

Received 16 May 2012; Accepted 3 July 2012

Academic Editor: Vitor Costa

Copyright © 2012 Patricia Back et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [35 citations]

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  • Christiaan F. Labuschagne, and Arjan B. Brenkman, “Current methods in quantifying ROS and oxidative damage in Caenorhabditis elegans and other model organism of aging,” Ageing Research Reviews, 2013. View at Publisher · View at Google Scholar
  • Grace Y. S. Goh, Katherine L. Martelli, Kulveer S. Parhar, Ada W. L. Kwong, Marcus A. Wong, Allan Mah, Nicole S. Hou, and Stefan Taubert, “ The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans ,” Aging Cell, 2013. View at Publisher · View at Google Scholar
  • Asuka Nishino, Ryo Kanno, and Tetsuya Matsuura, “ The Role of Oxygen Intermediates in the Retention Time of Diacetyl Adaptation in the Nematode Caenorhabditis elegans ,” Journal of Experimental Zoology Part A: Ecological Genetics and Physiology, 2013. View at Publisher · View at Google Scholar
  • Jürgen Bereiter-Hahn, “Do we age because we have mitochondria?,” Protoplasma, 2013. View at Publisher · View at Google Scholar
  • Andrew R. Mendelsohn, and James W. Larrick, “Rejuvenation of Adult Stem Cells: Is Age-Associated Dysfunction Epigenetic?,” Rejuvenation Research, vol. 16, no. 2, pp. 152–157, 2013. View at Publisher · View at Google Scholar
  • Bedoor Qabazard, Ling Li, Jan Gruber, Meng Teng Peh, Li Fang Ng, Srinivasan Dinesh Kumar, Peter Rose, Choon-Hong Tan, Brian W. Dymock, Feng Wei, Suresh C. Swain, Barry Halliwell, Stephen R. Stürzenbaum, and Philip K. Moore, “ Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans ,” Antioxidants & Redox Signaling, pp. 131121072603008, 2013. View at Publisher · View at Google Scholar
  • Gustavo Barja, “Updating the Mitochondrial Free Radical Theory of Aging: An Integrated View, Key Aspects, and Confounding Concepts,” Antioxidants & Redox Signaling, vol. 19, no. 12, pp. 1420–1445, 2013. View at Publisher · View at Google Scholar
  • V. A. Chistyakov, Yu. O. Smirnova, E. V. Prazdnova, and A. V. Soldatov, “Possible Mechanisms of Fullerene C60 Antioxidant Action,” BioMed Research International, vol. 2013, pp. 1–4, 2013. View at Publisher · View at Google Scholar
  • Natascha Castelein, Michael Muschol, Ineke Dhondt, Huaihan Cai, Winnok H. De Vos, Norbert A. Dencher, and Bart P. Braeckrnan, “Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans,” Experimental Gerontology, vol. 56, pp. 26–36, 2014. View at Publisher · View at Google Scholar
  • Brenna S. McCauley, and Weiwei Dang, “Histone methylation and aging: Lessons learned from model systems,” Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2014. View at Publisher · View at Google Scholar
  • Yu Sanada, Shota Asai, Atsumi Ikemoto, Takahito Moriwaki, Nobuya Nakamura, Masahiro Miyaji, and Qiu-Mei Zhang-Akiyama, “ Oxidation resistance 1 (OXR1) is essential for protection against oxidative stress and participates in the regulation of aging in Caenorhabditis elegans ,” Free Radical Research, pp. 1–27, 2014. View at Publisher · View at Google Scholar
  • Veronika Michalkova, Geoffrey M. Attardo, Jan Medlock, and Serap Aksoy, “Amelioration of Reproduction-Associated Oxidative Stress in a Viviparous Insect Is Critical to Prevent Reproductive Senescence,” Plos One, vol. 9, no. 4, 2014. View at Publisher · View at Google Scholar
  • P Jiang Ping, “Vascular Aging and The Corresponding Mechanisms,” Progress in Biochemistry and Biophysics, vol. 41, no. 3, pp. 295–304, 2014. View at Publisher · View at Google Scholar
  • Leanne Sandieson, Jason T.K. Hwang, and Gregory M. Kelly, “Redox Regulation of Canonical Wnt Signaling Affects Extraembryonic Endoderm Formation,” Stem Cells and Development, pp. 140311125028009, 2014. View at Publisher · View at Google Scholar
  • Sin-Gu Jeong, and Goang-Won Cho, “Trichostatin a modulates intracellular reactive oxygen species through SOD2 and FOXO1 in human bone marrow-mesenchymal stem cells,” Cell Biochemistry and Function, 2014. View at Publisher · View at Google Scholar
  • Annette O. Estevez, Kathleen L. Morgan, Nathaniel J. Szewczyk, David Gems, and Miguel Estevez, “The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans,” NeuroToxicology, 2014. View at Publisher · View at Google Scholar
  • Gary J. Hunter, Chi H. Trinh, Rosalin Bonetta, Emma E. Stewart, Diane E. Cabelli, and Therese Hunter, “ The structure of the Caenorhabditis elegans manganese superoxide dismutase MnSOD-3-azide complex ,” Protein Science, 2015. View at Publisher · View at Google Scholar
  • Timothy Truong, Zachary A. Karlinski, Christopher O'Hara, Maleen Cabe, Hongkyun Kim, and Joanna C. Bakowska, “Oxidative Stress in Caenorhabditis elegans: Protective Effects of Spartin,” Plos One, vol. 10, no. 6, 2015. View at Publisher · View at Google Scholar
  • Jan Gruber, Ce-Belle Chen, Sheng Fong, Li Fang Ng, Emelyne Teo, and Barry Halliwell, “ Caenorhabditis elegans : What We Can and Cannot Learn from Aging Worms ,” Antioxidants & Redox Signaling, pp. 150429074209008, 2015. View at Publisher · View at Google Scholar
  • Jiyun Lee, Gayeung Kwon, and Young-Hee Lim, “Elucidating the Mechanism of Weissella-dependent Lifespan Extension in Caenorhabditis elegans,” Scientific Reports, vol. 5, 2015. View at Publisher · View at Google Scholar
  • B A Martinez, H Kim, A Ray, G A Caldwell, and K A Caldwell, “A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans,” Cell Death and Disease, vol. 6, no. 10, pp. e1908, 2015. View at Publisher · View at Google Scholar
  • Injeong Cho, Gyu Jin Hwang, and Jeong Hoon Cho, “Uncoupling protein, UCP-4 may be involved in neuronal defects during aging and resistance to pathogens in Caenorhabditis elegans,” Molecules and Cells, vol. 39, no. 9, pp. 680–686, 2016. View at Publisher · View at Google Scholar
  • Patricia Martorell, Silvia Llopis, Nuria Gonzalez, Daniel Ramón, Gabriel Serrano, Ana Torrens, Juan M. Serrano, Maria Navarro, and Salvador Genovés, “ A nutritional supplement containing lactoferrin stimulates the immune system, extends lifespan, and reduces amyloid β peptide toxicity in Caenorhabditis elegans ,” Food Science & Nutrition, vol. 5, no. 2, pp. 255–265, 2016. View at Publisher · View at Google Scholar
  • Jennifer Watts, “Using Caenorhabditis elegans to Uncover Conserved Functions of Omega-3 and Omega-6 Fatty Acids,” Journal of Clinical Medicine, vol. 5, no. 2, pp. 19, 2016. View at Publisher · View at Google Scholar
  • Swati Srivastava, Aakanksha Pant, Shalini Trivedi, and Rakesh Pandey, “Curcumin and β-caryophellene attenuate cadmium quantum dots induced oxidative stress and lethality in Caenorhabditis elegans model system,” Environmental Toxicology and Pharmacology, 2016. View at Publisher · View at Google Scholar
  • Ilze Skujina, Robert McMahon, Vasileios Panagiotis E. Lenis, Georgios V. Gkoutos, and Matthew Hegarty, “Duplication of the mitochondrial control region is associated with increased longevity in birds,” Aging, vol. 8, no. 8, pp. 1781–1789, 2016. View at Publisher · View at Google Scholar
  • Arwen W. Gao, Jelmi uit de Bos, Mark G. Sterken, Jan E. Kammenga, Reuben L. Smith, and Riekelt H. Houtkooper, “Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans,” Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017. View at Publisher · View at Google Scholar
  • Jeremiah D. Keyes, Derek Parsonage, Rama D. Yammani, Le Ann C. Rogers, Chelsea Kesty, Cristina M. Furdui, Kimberly J. Nelson, and Leslie B. Poole, “Endogenous, Regulatory Cysteine Sulfenylation of ERK Kinases in Response to Proliferative Signals,” Free Radical Biology and Medicine, 2017. View at Publisher · View at Google Scholar
  • Ivan Gusarov, Bibhusita Pani, Laurent Gautier, Olga Smolentseva, Svetlana Eremina, Ilya Shamovsky, Olga Katkova-Zhukotskaya, Alexander Mironov, and Evgeny Nudler, “Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress,” Nature Communications, vol. 8, pp. 15868, 2017. View at Publisher · View at Google Scholar
  • Run-ting Huang, Qing Huang, Gen-liang Wu, Chun-guang Chen, and Zong-jun Li, “Evaluation of the antioxidant property and effects in Caenorhabditis elegans of Xiangxi flavor vinegar, a Hunan local traditional vinegar,” Journal of Zhejiang University: Science B, vol. 18, no. 4, pp. 324–333, 2017. View at Publisher · View at Google Scholar
  • Ricardo Laranjeiro, Girish Harinath, Daniel Burke, Bart P. Braeckman, and Monica Driscoll, “Single swim sessions in C. elegans induce key features of mammalian exercise,” BMC Biology, vol. 15, no. 1, 2017. View at Publisher · View at Google Scholar
  • Luisa Diomede, Margherita Romeo, Paola Rognoni, Marten Beeg, Claudia Foray, Elena Ghibaudi, Giovanni Palladini, Robert A. Cherny, Laura Verga, Gian Luca Capello, Vittorio Perfetti, Fabio Fiordaliso, Giampaolo Merlini, and Mario Salmona, “Cardiac Light Chain Amyloidosis: The Role of Metal Ions in Oxidative Stress and Mitochondrial Damage,” Antioxidants & Redox Signaling, 2017. View at Publisher · View at Google Scholar
  • Sin-Gu Jeong, Youn Seo Oh, I-Seul Joe, So Young Jeong, Hyo Moon Cho, Jun Sik Lee, Won Keun Oh, Tae Oh Cho, and Goang-Won Cho, “ Functional restoration of replicative senescent mesenchymal stem cells by the brown alga Undaria pinnatifida ,” Animal Cells and Systems, vol. 21, no. 2, pp. 108–114, 2017. View at Publisher · View at Google Scholar
  • Rachel Abergel, Leonid Livshits, Maayan Shaked, Arijit Kumar Chatterjee, and Einav Gross, “ Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans ,” Aging Cell, 2017. View at Publisher · View at Google Scholar
  • Collin Yvès Ewald, John M Hourihan, Monet S Bland, Carolin Obieglo, Iskra Katic, Lorenza E Moronetti Mazzeo, Joy Alcedo, T Keith Blackwell, and Nancy E Hynes, “ NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans ,” eLife, vol. 6, 2017. View at Publisher · View at Google Scholar