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Oxidative Medicine and Cellular Longevity
Volume 2013, Article ID 513742, 9 pages
http://dx.doi.org/10.1155/2013/513742
Clinical Study

The Effect of High-Dose Insulin Analog Initiation Therapy on Lipid Peroxidation Products and Oxidative Stress Markers in Type 2 Diabetic Patients

1Department of Medical Biochemistry, Akdeniz University Medical School, 07070 Antalya, Turkey
2Endocrinology Clinic, Antalya Research and Education Hospital, 07100 Antalya, Turkey

Received 29 December 2012; Revised 16 February 2013; Accepted 18 February 2013

Academic Editor: Kota V. Ramana

Copyright © 2013 Hazal Tuzcu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. UK Prospective Diabetes Study (UKPDS) Group, “Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33),” Lancet, vol. 352, no. 9131, pp. 837–853, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. The Diabetes Control and Complications Trial Research Group, “The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus,” The New England Journal of Medicine, vol. 329, pp. 977–986, 1993. View at Google Scholar
  3. A. Ceriello, M. Hanefeld, L. Leiter et al., “Postprandial glucose regulation and diabetic complications,” Archives of Internal Medicine, vol. 164, no. 19, pp. 2090–2095, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Ceriello, K. Esposito, L. Piconi et al., “Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients,” Diabetes, vol. 57, no. 5, pp. 1349–1354, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Brownlee and I. B. Hirsch, “Glycemic variability: a hemoglobin A1c-independent risk factor for diabetic complications,” Journal of the American Medical Association, vol. 295, no. 14, pp. 1707–1708, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. J. L. Chiasson, R. G. Josse, R. Gomis, M. Hanefeld, A. Karasik, and M. Laakso, “Acarbose Treatment and the Risk of Cardiovascular Disease and Hypertension in Patients with Impaired Glucose Tolerance: The STOP-NIDDM Trial,” Journal of the American Medical Association, vol. 290, no. 4, pp. 486–494, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. R. De Caterina, “Endothelial dysfunctions: common denominators in vascular disease,” Current Opinion in Lipidology, vol. 11, no. 1, pp. 9–23, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Ceriello, C. Taboga, L. Tonutti et al., “Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment,” Circulation, vol. 106, no. 10, pp. 1211–1218, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Brownlee, “Biochemistry and molecular cell biology of diabetic complications,” Nature, vol. 414, no. 6865, pp. 813–820, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Rodbard, “Optimizing display, analysis, interpretation and utility of self-monitoring of blood glucose (SMBG) data for management of patients with diabetes,” Journal of Diabetes Science and Technology, vol. 1, pp. 62–71, 2007. View at Google Scholar
  11. G. McGarraugh, “The chemistry of commercial continuous glucose monitors,” Diabetes technology & therapeutics, vol. 11, pp. S17–S24, 2009. View at Google Scholar · View at Scopus
  12. H. W. Rodbard, L. Blonde, S. S. Braithwaite et al., “American association of clinical endocrinologists medical guidelines for clinical practice for the management of diabetes mellitus,” Endocrine Practice, vol. 13, no. 1, pp. 1–68, 2007. View at Google Scholar · View at Scopus
  13. A. Kupesiz, G. Celmeli, S. Dogan, B. Antmen, and M. Aslan, “The effect of hemolysis on plasma oxidation and nitration in patients with sickle cell disease,” Free Radical Research, vol. 46, pp. 883–890, 2012. View at Google Scholar
  14. L. Monnier, E. Mas, C. Ginet et al., “Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes,” Journal of the American Medical Association, vol. 295, no. 14, pp. 1681–1687, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. I. M. E. Wentholt, W. Kulik, R. P. J. Michels, J. B. L. Hoekstra, and J. H. DeVries, “Glucose fluctuations and activation of oxidative stress in patients with type 1 diabetes,” Diabetologia, vol. 51, no. 1, pp. 183–190, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. S. E. Siegelaar, T. Barwari, W. Kulik, J. B. Hoekstra, and H. J. DeVries, “No relevant relationship between glucose variability and oxidative stress in well-regulated type 2 diabetes patients,” Journal of diabetes science and technology, vol. 5, no. 1, pp. 86–92, 2011. View at Google Scholar · View at Scopus
  17. P. Odetti, S. Garibaldi, G. Noberasco et al., “Levels of carbonyl groups in plasma proteins of type 2 diabetes mellitus subjects,” Acta Diabetologica, vol. 36, no. 4, pp. 179–183, 1999. View at Google Scholar · View at Scopus
  18. U. Çakatay, “Protein oxidation parameters in type 2 diabetic patients with good and poor glycaemic control,” Diabetes and Metabolism, vol. 31, no. 6, pp. 551–557, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Z. Pan, H. Zhang, D. Chang, H. Li, and H. Sui, “The change of oxidative stress products in diabetes mellitus and diabetic retinopathy,” British Journal of Ophthalmology, vol. 92, no. 4, pp. 548–551, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Z. Pan, L. Zhang, M. Y. Guo et al., “The oxidative stress status in diabetes mellitus and diabetic nephropathy,” Acta Diabetologica, vol. 47, no. 1, pp. S71–S76, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Sarkar, K. Kar, M. C. Mondal, I. Chakraborty, and M. Kar, “Elevated level of carbonyl compounds correlates with insulin resistance in type 2 diabetes,” Annals of the Academy of Medicine Singapore, vol. 39, no. 12, pp. 909–912, 2010. View at Google Scholar · View at Scopus
  22. E. C. Pereira, S. Ferderbar, M. C. Bertolami et al., “Biomarkers of oxidative stress and endothelial dysfunction in glucose intolerance and diabetes mellitus,” Clinical Biochemistry, vol. 41, no. 18, pp. 1454–1460, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Ceriello, F. Mercuri, L. Quagliaro et al., “Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress,” Diabetologia, vol. 44, no. 7, pp. 834–838, 2001. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Ceriello, L. Quagliaro, B. Catone et al., “Role of hyperglycemia in nitrotyrosine postprandial generation,” Diabetes Care, vol. 25, no. 8, pp. 1439–1443, 2002. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Predescu, S. Predescu, and A. B. Malik, “Transport of nitrated albumin across continuous vascular endothelium,” Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 21, pp. 13932–13937, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. F. Zheng, W. Lu, C. Jia, H. Li, Z. Wang, and W. Jia, “Relationships between glucose excursion and the activation of oxidative stress in patients with newly diagnosed type 2 diabetes or impaired glucose regulation,” Endocrine, vol. 37, no. 1, pp. 201–208, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. L. Monnier, C. Colette, E. Mas et al., “Regulation of oxidative stress by glycaemic control: Evidence for an independent inhibitory effect of insulin therapy,” Diabetologia, vol. 53, no. 3, pp. 562–571, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Sakamoto, G. Inoue, K. Tsuyusaki et al., “Comparison of oxidative stress markers in type 2 diabetes: Basal bolus therapy versus twice daily premixed insulin analogs,” Internal Medicine, vol. 49, no. 5, pp. 355–359, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. L. Monnier, C. Colette, F. Michel, J. P. Cristol, and D. R. Owens, “Insulin therapy has a complex relationship with measure of oxidative stress in type 2 diabetes: a case for further study,” Diabetes/Metabolism Research and Reviews, vol. 27, no. 4, pp. 348–353, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. S. F. Nunes, I. V. Figueiredo, P. J. Soares, N. E. Costa, M. C. Lopes, and M. M. Caramona, “Semicarbazide-sensitive amine oxidase activity and total nitrite and nitrate concentrations in serum: Novel biochemical markers for type 2 diabetes?” Acta Diabetologica, vol. 46, no. 2, pp. 135–140, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Catalano, G. Carzaniga, E. Perilli et al., “Basal nitric oxide production is not reduced in patients with noninsulin-dependent diabetes mellitus,” Vascular Medicine, vol. 2, no. 4, pp. 302–305, 1997. View at Google Scholar · View at Scopus
  32. F. Francesconi, R. Mingardi, S. DeKreutzenberg, and A. Avogaro, “Effect of metabolic control on nitrite and nitrate metabolism in type 2 diabetic patients,” Clinical and Experimental Pharmacology and Physiology, vol. 28, no. 7, pp. 518–521, 2001. View at Publisher · View at Google Scholar · View at Scopus