Oxidative Stress Is Predominant in Female but Not in Male Patients with Autoimmune Thrombocytopenia

Table 2

Combinations of oxidative stress and antioxidant capacities in AITP patients and controls. As demonstrated in Table 2, all patients without OS had normal or good AOCs, whereas two healthy controls had reduced AOCs. Overall, 19 controls did not demonstrate OS, in comparison to only nine patients. Interestingly, 14 patients demonstrated strong levels of OS, in comparison to only four healthy controls. However, only 5 of 37 (13.5%) patients demonstrated a pathological combination (strong OS, reduced AOCs), with a higher tendency towards oxidative damage. OS: oxidative stress; AOCs: antioxidant capacities; 𝑛: number; AITP: autoimmune thrombocytopenia.

Combinations	AITP	Controls
No OS
Normal or good AOC	𝑛=9	𝑛=17
Reduced AOC	𝑛=0	𝑛=2
Moderate OS
Normal or good AOC	𝑛=11	𝑛=11
Reduced AOC	𝑛=3	𝑛=3
Strong OS
Normal or good AOC	𝑛=9	𝑛=3
Reduced AOC	𝑛=5	𝑛=1