Nrf2 Deficiency Exaggerates Doxorubicin-Induced Cardiotoxicity and Cardiac Dysfunction
Figure 2
Dox-induced autophagic activity in the heart. Male 10–12 wk old WT mice (C57BL/6J) were treated as in Figure 1, and then hearts ( for each group at indicated time point) were harvested for Western blot analysis. (a) Representatives of immunoblots as indicated. (b) Semiquantified analysis of protein expression as indicated (). versus Veh in the same experimental group.