Exercise-Induced Neuroprotection of Hippocampus in APP/PS1 Transgenic Mice via Upregulation of Mitochondrial 8-Oxoguanine DNA Glycosylase

Figure 3

Effects of 20 weeks of treadmill exercise training on mitochondrial state 3 respiration rate (a), state 4 respiration rate (b), and respiratory control ratio (RCR) (c). Group identities are the same as those in Figure 1. Hippocampus from four mice in one group was pooled and mitochondria were isolated for each sample, for all independent experiments. Data are mean ± SD. ; , compared to SED-WT group. , compared to SED-Wt or SED-Tg group. n.s., nonsignificant.

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