Oxidative Medicine and Cellular Longevity
Volume 2015 (2015), Article ID 157876, 8 pages
http://dx.doi.org/10.1155/2015/157876
Research Article
Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain
Laboratory of “Drug Metabolism and Drug Toxicity”, Department of “Pharmacology, Pharmacotherapy and Toxicology”, Faculty of Pharmacy, Medical University of Sofia, 2 “Dunav” Street, 1000 Sofia, Bulgaria
Received 30 December 2014; Revised 24 March 2015; Accepted 26 March 2015
Academic Editor: Joern Steinert
Copyright © 2015 Vessela Vitcheva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- K. F. Foley, “Mechanism of action and therapeutic uses of psychostimulants,” Clinical Laboratory Science, vol. 18, no. 2, pp. 107–113, 2005. View at Google Scholar
- P. Kovacic, “Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer,” Medical Hypotheses, vol. 64, no. 2, pp. 350–356, 2005. View at Publisher · View at Google Scholar · View at Scopus
- I. Riezzo, C. Fiore, D. De Carlo et al., “Side effects of cocaine abuse: multiorgan toxicity and pathological consequences,” Current Medicinal Chemistry, vol. 19, no. 33, pp. 5624–5646, 2012. View at Publisher · View at Google Scholar · View at Scopus
- T. Cunha-Oliveira, A. C. Rego, F. Carvalho, and C. R. Oliveira, “Medical toxicology of drugs of abuse,” in Principles of Addiction-Comprehensive Addictive Behaviors and Disorders, P. Miller, Ed., vol. 1, pp. 159–175, Academic Press, 2013. View at Google Scholar
- W.-M. Lue, M.-T. Su, W.-B. Lin, and P.-L. Tao, “The role of nitric oxide in the development of morphine tolerance in rat hippocampal slices,” European Journal of Pharmacology, vol. 383, no. 2, pp. 129–135, 1999. View at Publisher · View at Google Scholar · View at Scopus
- Y. Itzhak and S. F. Ali, “Role of nitrergic system in behavioral and neurotoxic effects of amphetamine analogs,” Pharmacology & Therapeutics, vol. 109, no. 1-2, pp. 246–262, 2006. View at Publisher · View at Google Scholar · View at Scopus
- F. X. Guix, I. Uribesalgo, M. Coma, and F. J. Muñoz, “The physiology and pathophysiology of nitric oxide in the brain,” Progress in Neurobiology, vol. 76, no. 2, pp. 126–152, 2005. View at Publisher · View at Google Scholar · View at Scopus
- C. F. B. Witteveen, J. Giovanelli, and S. Kaufman, “Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase,” The Journal of Biological Chemistry, vol. 271, no. 8, pp. 4143–4147, 1996. View at Publisher · View at Google Scholar · View at Scopus
- Y. Itzhak, “Modulation of cocaine- and methamphetamine-induced behavioral sensitization by inhibition of brain nitric acid oxide,” Journal of Pharmacology and Experimental Therapeutics, vol. 282, no. 2, pp. 521–527, 1997. View at Google Scholar · View at Scopus
- S. F. Ali and Y. Itzhak, “Effects of 7-nitroindazole, an NOS inhibitor on methamphetamine-induced dopaminergic and serotonergic neurotoxicity in mice,” Annals of the New York Academy of Sciences, vol. 844, pp. 122–130, 1998. View at Publisher · View at Google Scholar · View at Scopus
- I. T. Uzbay, B. F. Erden, E. E. Tapanyigit, and S. O. Kayaalp, “Nitric oxide synthase inhibition attenuates signs of ethanol withdrawal in rats,” Life Sciences, vol. 61, no. 22, pp. 2197–2209, 1997. View at Publisher · View at Google Scholar · View at Scopus
- S. L. Collins and K. M. Kantak, “Neuronal nitric oxide synthase inhibition decreases cocaine self-administration behavior in rats,” Psychopharmacology, vol. 159, no. 4, pp. 361–369, 2002. View at Publisher · View at Google Scholar · View at Scopus
- Council of Europe, “European convention for the protection of vertebrate animals used for experimental and other scientific purposes,” CETS 123, 1991. View at Google Scholar
- R. A. Gregg, C. S. Tallarida, A. B. Reitz, and S. M. Rawls, “Mephedrone interactions with cocaine: prior exposure to the ‘bath salt’ constituent enhances cocaine-induced locomotor activation in rats,” Behavioural Pharmacology, vol. 24, no. 8, pp. 684–688, 2013. View at Publisher · View at Google Scholar · View at Scopus
- S. Irwin, “Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse,” Psychopharmacologia, vol. 13, no. 3, pp. 222–257, 1968. View at Publisher · View at Google Scholar · View at Scopus
- R. G. Knowles and S. Moncada, “Nitric oxide synthases in mammals,” Biochemical Journal, vol. 298, no. 2, pp. 249–258, 1994. View at Google Scholar · View at Scopus
- O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randall, “Protein measurement with the Folin phenol reagent,” The Journal of Biological Chemistry, vol. 193, no. 1, pp. 265–275, 1951. View at Google Scholar · View at Scopus
- C. Deby and R. Goutier, “New perspectives on the biochemistry of superoxide anion and the efficiency of superoxide dismutases,” Biochemical Pharmacology, vol. 39, no. 3, pp. 399–405, 1990. View at Publisher · View at Google Scholar · View at Scopus
- E. A. Bump, Y. C. Taylor, and J. M. Brown, “Role of glutathione in the hypoxic cell cytotoxicity of misonidazole,” Cancer Research, vol. 43, no. 3, pp. 997–1002, 1983. View at Google Scholar · View at Scopus
- H. Aebi, “Catalase,” in Methods of Enzymatic Analysis, H. U. Bergrenyer, Ed., pp. 673–684, Academic Press, New York, NY, USA, 2nd edition, 1974. View at Google Scholar
- H. P. Misra and I. Fridovich, “The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase,” The Journal of Biological Chemistry, vol. 247, no. 10, pp. 3170–3175, 1972. View at Google Scholar · View at Scopus
- A. L. Tappel, “Glutathione peroxidase and hydroperoxydes,” Methods in Enzymology, vol. 52, pp. 506–513, 1978. View at Google Scholar
- M. C. Pinto, A. M. Mata, and J. Lopez-barea, “Reversible inactivation of Saccharomyces cerevisiae glutathione reductase under reducing conditions,” Archives of Biochemistry and Biophysics, vol. 228, no. 1, pp. 1–12, 1984. View at Publisher · View at Google Scholar · View at Scopus
- W. H. Habig, M. J. Pabst, and W. B. Jakoby, “Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation,” The Journal of Biological Chemistry, vol. 249, no. 22, pp. 7130–7139, 1974. View at Google Scholar · View at Scopus
- P. Taupin, S. Zini, F. Cesselin, Y. Ben-Ari, and M.-P. Roisin, “Subcellular fractionation on Percoll gradient of mossy fiber synaptosomes: morphological and biochemical characterization in control and degranulated rat hippocampus,” Journal of Neurochemistry, vol. 62, no. 4, pp. 1586–1595, 1994. View at Google Scholar · View at Scopus
- X. Mungarro-Menchaca, P. Ferrera, J. Morán, and C. Arias, “β-amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine,” Journal of Neuroscience Research, vol. 68, no. 1, pp. 89–96, 2002. View at Publisher · View at Google Scholar
- J. F. Robyt, R. J. Ackerman, and C. G. Chittenden, “Reaction of protein disulfide groups with Ellman's reagent: a case study of the number of sulfhydryl and disulfide groups in Aspergillus oryzaeα-amylase, papain, and lysozyme,” Archives of Biochemistry and Biophysics, vol. 147, no. 1, pp. 262–269, 1971. View at Publisher · View at Google Scholar · View at Scopus
- American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, vol. 1, American Psychiatric Association, Arlington, Va, USA, 4th edition, 2000. View at Publisher · View at Google Scholar
- V. Bashkatova, J. Meunier, A. Vanin, and T. Maurice, “Nitric oxide and oxidative stress in the brain of rats exposed in utero to cocaine,” Annals of the New York Academy of Sciences, vol. 1074, pp. 632–642, 2006. View at Publisher · View at Google Scholar · View at Scopus
- H. F. Poon, L. Abdullah, M. A. Mullan, M. J. Mullan, and F. C. Crawford, “Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells,” Neurochemistry International, vol. 50, no. 1, pp. 69–73, 2007. View at Publisher · View at Google Scholar · View at Scopus
- A. O. Sordi, F. Pechansky, F. H. P. Kessler et al., “Oxidative stress and BDNF as possible markers for the severity of crack cocaine use in early withdrawal,” Psychopharmacology, vol. 231, no. 20, pp. 4031–4039, 2014. View at Publisher · View at Google Scholar · View at Scopus
- J.-B. Dietrich, A. Mangeol, M.-O. Revel, C. Burgun, D. Aunis, and J. Zwiller, “Acute or repeated cocaine administration generates reactive oxygen species and induces antioxidant enzyme activity in dopaminergic rat brain structures,” Neuropharmacology, vol. 48, no. 7, pp. 965–974, 2005. View at Publisher · View at Google Scholar · View at Scopus
- E. J. Nestler, “Historical review: molecular and cellular mechanisms of opiate and cocaine addiction,” Trends in Pharmacological Sciences, vol. 25, no. 4, pp. 210–218, 2004. View at Publisher · View at Google Scholar · View at Scopus
- I. Fridovich, “Superoxide dismutases,” Advances in Enzymology and Related Areas of Molecular Biology, vol. 58, pp. 61–97, 1986. View at Google Scholar · View at Scopus
- W.-M. Lue, M.-T. Su, W.-B. Lin, and P.-L. Tao, “The role of nitric oxide in the development of morphine tolerance in rat hippocampal slices,” European Journal of Pharmacology, vol. 383, no. 2, pp. 129–135, 1999. View at Publisher · View at Google Scholar · View at Scopus
- J. L. Haracz, J. S. MacDonall, and R. Sircar, “Effects of nitric oxide synthase inhibitors on cocaine sensitization,” Brain Research, vol. 746, no. 1-2, pp. 183–189, 1997. View at Publisher · View at Google Scholar · View at Scopus
- R. A. González-Polo, G. Soler, A. Rodríguezmartín, J. M. Morán, and J. M. Fuentes, “Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants,” Cell Biology International, vol. 28, no. 5, pp. 373–380, 2004. View at Publisher · View at Google Scholar · View at Scopus
- G.-L. Chu, Y. Xin, J. Cheng, and S.-Y. Bi, “Expression of neuronal nitric oxide synthase in brain tissue of hypoxic-ischemic neonatal rat and the cerebral protective effect of neuronal nitric oxide synthase inhibitor 7-nitroindazole,” Zhonghua yi xue za zhi, vol. 84, no. 2, pp. 156–158, 2004. View at Google Scholar · View at Scopus
- J. E. Royland, K. Delfani, J. W. Langston, A. M. Janson, and D. A. di Monte, “7-Nitroindazole prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced ATP loss in the mouse striatum,” Brain Research, vol. 839, no. 1, pp. 41–48, 1999. View at Publisher · View at Google Scholar · View at Scopus
- D. A. Di Monte, J. E. Royland, A. Anderson, K. Castagnoli, N. Castagnoli Jr., and J. W. Langston, “Inhibition of monoamine oxidase contributes to the protective effect of 7-nitroindazole against MPTP neurotoxicity,” Journal of Neurochemistry, vol. 69, no. 4, pp. 1771–1773, 1997. View at Google Scholar · View at Scopus