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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 8715185, 11 pages
Research Article

Nephroprotective Effects of N-Acetylcysteine Amide against Contrast-Induced Nephropathy through Upregulating Thioredoxin-1, Inhibiting ASK1/p38MAPK Pathway, and Suppressing Oxidative Stress and Apoptosis in Rats

1Department of Nephrology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Middle Road, Shanghai 200071, China
2Department of Women’s and Children’s Health, Karolinska Institutet, Karolinska University Hospital, 171 77 Stockholm, Sweden
3Center for Radiological Research, Department of Radiation Oncology, College of Physician and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA

Received 1 October 2016; Accepted 30 November 2016

Academic Editor: Mohamed M. Abdel-Daim

Copyright © 2016 Xuezhong Gong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Svante Norgren, and Xue-zhong Gong, “Contrast-induced nephropathy—time for Western medicine and Chinese medicine to team up,” Chinese Journal of Integrative Medicine, 2017. View at Publisher · View at Google Scholar
  • Ningning Guo, Xianwen Zhang, Mengbing Huang, Xiang Li, Ye Li, Xiaoshuang Zhou, and Jie Bai, “Geranylgeranylacetone blocks the reinstatement of morphine conditioned place preference,” Neuropharmacology, 2018. View at Publisher · View at Google Scholar
  • Jing-si Zhou, Zhou Zhu, Feng Wu, Ying Zhou, Rui Sheng, Jun-chao Wu, and Zheng-hong Qin, “NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation,” Acta Pharmacologica Sinica, 2018. View at Publisher · View at Google Scholar
  • Xue-zhong Gong, “Recent advances in Chinese medicine for contrast-induced nephropathy,” Chinese Journal of Integrative Medicine, vol. 24, no. 1, pp. 6–9, 2018. View at Publisher · View at Google Scholar
  • Nana Liu, Jing Chen, Dongmei Gao, Wenhua Li, and Di Zheng, “Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression,” International Urology and Nephrology, 2018. View at Publisher · View at Google Scholar