Table of Contents Author Guidelines Submit a Manuscript
Oxidative Medicine and Cellular Longevity
Volume 2017 (2017), Article ID 1372640, 16 pages
https://doi.org/10.1155/2017/1372640
Research Article

Mitochondrial Respiration in Human Colorectal and Breast Cancer Clinical Material Is Regulated Differently

1Laboratory of Bioenergetics, National Institute of Chemical Physics and Biophysics, Tallinn, Estonia
2Oncology and Haematology Clinic at the North Estonia Medical Centre, Tallinn, Estonia
3Laboratory of Fundamental and Applied Bioenergetics, INSERM, University Grenoble Alpes, U1055 Grenoble, France
4School of Natural Sciences and Health, Tallinn University, Tallinn, Estonia

Correspondence should be addressed to Tuuli Kaambre

Received 27 January 2017; Revised 10 April 2017; Accepted 19 April 2017; Published 11 July 2017

Academic Editor: Moh H. Malek

Copyright © 2017 Andre Koit et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Table 1. Activity of citrate synthase as marker of mitochondrial mass [105], in human breast and colorectal cancers as well as in corresponding normal tissues. Enzymatic activity measured as mU/mg protein, mean ± SE. Supplementary Fig. 1. Quantification of Complex I subunit NDUFA9 expression levels using Western blot (WB) and anti-NDUFA9 antibody in HCC and healthy colon tissue samples (A); respective WB image of NDUFA9 protein levels (B). Levels of NDUFA9 were normalized to total protein content quantified by coomassie blue staining. Data are represented as mean values ± SEM from 4 independent experiments; * p<0.05.

  1. Supplementary Material