Oxidative Medicine and Cellular Longevity

Mitochondrial Structure, Function, and Dynamics: The Common Thread across Organs, Disease, and Aging


Status
Published

Lead Editor

1Wayne State University, Detroit, USA

2Dankook University, Yongin-si, Republic of Korea


Mitochondrial Structure, Function, and Dynamics: The Common Thread across Organs, Disease, and Aging

Description

Mitochondria are central to all basic and advanced cellular and organismal functions. In addition to the vast majority of cellular energy generated by these unique organelles, they are also essential signaling hubs and communicate with the rest of the cell through various means including reactive oxygen species. Their dysfunction is implicated in essentially all common diseases ranging from neuromuscular disease to diabetes and cancer.

The aim of this special issue is to provide the readership with current examples of how mitochondria function and how different adverse conditions result in their dysfunction. Therefore, we invite scientists to contribute original research as well as review articles ranging from basic science to clinical studies. Moreover, we welcome studies that focus on the role of mitochondria in various organs such as, but not limited to, the brain, heart, liver, kidney, reproductive organs, and muscle.

Potential topics include but are not limited to the following:

  • Role of inflammation on mitochondrial structure, function, and/or dynamics
  • Role of aging on mitochondria structure, function, and/or dynamics
  • Role of environmental pollutants/toxins on mitochondrial structure, function, and/or dynamics
  • Regulation of energy metabolism and the production of reactive oxygen species
  • Tissue-specific mitochondrial dysfunction across various organs
  • Countermeasures to mitochondrial dysfunction resulting from a disease
  • Apoptosis

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 1863414
  • - Editorial

Mitochondrial Structure, Function, and Dynamics: The Common Thread across Organs, Disease, and Aging

Moh H. Malek | Maik Hüttemann | Icksoo Lee
  • Special Issue
  • - Volume 2018
  • - Article ID 6451902
  • - Research Article

ZP2495 Protects against Myocardial Ischemia/Reperfusion Injury in Diabetic Mice through Improvement of Cardiac Metabolism and Mitochondrial Function: The Possible Involvement of AMPK-FoxO3a Signal Pathway

Shuang Li | Hao Wu | ... | Feng Cao
  • Special Issue
  • - Volume 2017
  • - Article ID 9302761
  • - Research Article

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease

Patricia Martín-Maestro | Ricardo Gargini | ... | Vega García-Escudero
  • Special Issue
  • - Volume 2017
  • - Article ID 7317251
  • - Research Article

Blood-Based Bioenergetic Profiling Reflects Differences in Brain Bioenergetics and Metabolism

Daniel J. Tyrrell | Manish S. Bharadwaj | ... | Anthony J. A. Molina
  • Special Issue
  • - Volume 2017
  • - Article ID 1062314
  • - Research Article

Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups

Huaibin Zhou | Ke Nie | ... | Hezhi Fang
  • Special Issue
  • - Volume 2017
  • - Article ID 6412682
  • - Research Article

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis

Pia Rademann | Adelheid Weidinger | ... | Marcin F. Osuchowski
  • Special Issue
  • - Volume 2017
  • - Article ID 5213186
  • - Research Article

β-Naphthoflavone-Induced Mitochondrial Respiratory Damage in Cyp1 Knockout Mouse and in Cell Culture Systems: Attenuation by Resveratrol Treatment

Suresh Kumar Anandasadagopan | Naveen M. Singh | ... | Narayan G. Avadhani
  • Special Issue
  • - Volume 2017
  • - Article ID 1202459
  • - Research Article

Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized Rats

Wensheng Yan | Yunxiao Kang | ... | Geming Shi
  • Special Issue
  • - Volume 2017
  • - Article ID 3064016
  • - Research Article

Increased Mitochondrial Mass and Cytosolic Redox Imbalance in Hippocampal Astrocytes of a Mouse Model of Rett Syndrome: Subcellular Changes Revealed by Ratiometric Imaging of JC-1 and roGFP1 Fluorescence

Dörthe F. Bebensee | Karolina Can | Michael Müller
  • Special Issue
  • - Volume 2017
  • - Article ID 1697018
  • - Research Article

Caffeic Acid Phenethyl Ester Reduces Ischemia-Induced Kidney Mitochondrial Injury in Rats

Sonata Trumbeckaite | Neringa Pauziene | ... | Rasa Baniene
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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