Oxidative Medicine and Cellular Longevity

Review Article

Potential of Lichen Compounds as Antidiabetic Agents with Antioxidative Properties: A Review

Table 2

Antioxidant potential of lichens/compounds reported as antidiabetic.


Lichen extracts/compounds	Antioxidant activity [References]	Assayed bioactivity type

Flavoparmelia caperata	Stojanović et al., 2010 [51] Mitrović et al., 2011 [52]	DPPH & FRAP assays DPPH

Parmotrema reticulatum	Ghate et al., 2013 [53] Sharma, 2012 [54] Rajan et al., 2016 [55]	HORAC, ORAC, DPPH, SOI, & NOS DPPH & FRAP assays DPPH

Parmotrema tinctorum	Raj et al., 2014 [32] Vivek et al., 2014 [56] Rajan et al., 2016 [55]	DPPH, ABTS, SOI, HORAC DPPH DPPH

Parmotrema	Rajan et al., 2016 [55]	DPPH
Pseudotinctorum	Kumar et al., 2010 [57]	DPPH & FRAP
Parmotrema chinense	Vivek et al., 2014 [56]	DPPH

Everniastrum cirrhatum	Kekuda et al., 2011 [58] Kumar et al., 2014 [59]	DPPH, FRAP & MC DPPH & FRAP

Usnea sinensis	Prateeksha et al., 2016 [60] Devahat et al., 2007 [61]	DPPH

Ramalina pollinaria	Gulluce et al., 2006 [62]	DPPH & ALP

Ramalina celastri	Verma et al., 2012 [36]	DPPH, ALP, SOI, NOS & TEAC

R. nervulosa	Verma et al., 2012 [36]	DPPH, ALP, SOI, NOS & TEAC

R. pacifica	Verma et al., 2012 [36]	DPPH, ALP, SOI, NOS & TEAC

Ramalina conduplicans	Luo et al., 2010 [63] Xia et al., 2015 [64] Kumar et al., 2009 [65]	DPPH, FRAP & ALP DPPH & ABTS DPPH

Ramalina hossei	Kumar et al., 2009 [65] Ranković, 2015 [66]	DPPH DPPH

Punctelia subrudecta	Mastan et al., 2014, [67]	DPPH and HORAC
Peltigera praetextata	Zambare and Christopher 2012 [10]	DPPH and HORAC

Umbilicaria antarctica	Luo et al., 2009 [68]	DPPH, SOI, ALP
Umbilicaria antarctica	Strzalka et al., 2011 [69]	tocopherols, plastoquinone & plastochromanol

Stereocaulon alpinum	Bhattarai et al., 2008 [70] Bhattarai et al., 2013 [71]	DPPH DPPH
Caloplaca biatorina	Valadbeigi; 2016 [34]	DPPH, FRAP

Salazinic acid	Selvaraj et al.; 2015 [72]	DPPH, FRAP, MC, HORAC, ALP, phosphomolybdenum SOI
Salazinic acid	Manojlovic et al., 2012 [73]	DPPH, SOI
Gyrophoric acid	Kosanic et al., 2014 [74]	DPPH, SOI, FRAP

Sekikaic acid, Usnic acid Methyl-β-orcinol carboxylate Methylorsellinate Lecanoric acid Methylhaematomate Orsellinic acid, Lobaric acid, Divaricatic acid	Thadhani et al., 2011 [18]	DPPH, SOI, NOS & MC

DPPH: (1, 1diphenyl-2-picrylhydrazyl) radical scavenging method, FRAP: ferric reducing antioxidant power, MC: metal chelating, SOI: super oxide inhibitory, ALP: anti-linoleic acid peroxidation assay, NOS: nitric oxide-scavenging assay; TEAC: trolox equivalent antioxidant capacity assay; HORAC: hydroxyl radical antioxidant capacity, and ORAC: oxygen radical antioxidant capacity.