Oxidative Stress Delays Prometaphase/Metaphase of the First Cleavage in Mouse Zygotes via the MAD2L1-Mediated Spindle Assembly Checkpoint

<div><i>γ</i>H2AX detection in mouse zygotes at 17 hpi. Nuclei were stained with DAPI (blue). <i>γ</i>H2AX staining was detected in the nuclei of H<sub>2</sub>O<sub>2</sub>-treated embryos, but not in those of the control group.</div>

Oxidative Medicine and Cellular Longevity

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Figure 2

Figure 2: Oxidative Stress Delays Prometaphase/Metaphase of the First Cleavage in Mouse Zygotes via the MAD2L1-Mediated Spindle Assembly Checkpoint 