Oxidative Stress Delays Prometaphase/Metaphase of the First Cleavage in Mouse Zygotes via the MAD2L1-Mediated Spindle Assembly Checkpoint

Table 1

Ratio of H3S10P-expressing cells in control and treated zygotes from 18 hpi to 21 hpi.

Groups

18.0 (hpi)

18.5 (hpi)

19.0 (hpi)

19.5 (hpi)

20.0 (hpi)

20.5 (hpi)

21.0 (hpi)

21.5 (hpi)

22.0 (hpi)

22.5 (hpi)

23.0 (hpi)

23.5 (hpi)

24.0 (hpi)

Control

0/67

10/56

37/70

40/72

21/75

12/70

0/63

0

0

0

0

0

0

Treated

0/52

0/53

7/52

20/86

0/49

10/70

12/60

36/70

46/69

39/60

16/64

4/58

0

The treated group was administered 0.03 mM H₂O₂. Hpi: hours postinsemination.