Research Article

EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice

Figure 6

Relative CpG methylation status in promotor region of MLH1 in colon. Mean methylation data are shown for MLH1 as an overview (Figure 6(a)) (significant for CpG 1, 2, and 4) and CpG5 (Figure 6(b)). All methylation data are relative to CD. Error bars represent 95% confidence intervals (CD = control diet; HFD = high fat diet; CD + EGCG = control diet plus EGCG; HFD + EGCG = high fat diet plus EGCG; stars indicate significance: value ≤ 0.05 and value ≤ 0.01).
(a)
(b)