A Single Zidovudine (AZT) Administration Delays Hepatic Cell Proliferation by Altering Oxidative State in the Regenerating Rat Liver

Figure 3

Effects of AZT on parameters indicative of oxidant stress in the cytosolic fraction obtained from livers at various times after 70% PH. Results are expressed as mean ± SE for four independent determinations per experimental point as nmoles⋅mg⁻¹ of protein in panels (a) and (b), or in pmoles⋅mg⁻¹ of protein (panel (c)). Symbols for the experimental groups at the bottom of each figure and the statistical significance as indicated in Figure 1.

(a) MDA

(b) Carbonyl groups