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Oxidative Medicine and Cellular Longevity
Volume 2017, Article ID 9315375, 8 pages
Research Article

Influence of Synbiotics on Selected Oxidative Stress Parameters

Department of Immunopathology, Faculty of Biomedical Sciences and Postgraduate Training, Medical University of Lodz, 7/9 Zeligowskiego St, 90-752 Lodz, Poland

Correspondence should be addressed to Rafał Pawliczak; lp.zdol.demu.ksc@kazcilwap.lafar

Received 13 October 2016; Revised 21 December 2016; Accepted 15 January 2017; Published 13 February 2017

Academic Editor: Ilaria Peluso

Copyright © 2017 Paulina Kleniewska and Rafał Pawliczak. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aim of the present study was to assess synbiotic (Lactobacillus casei + inulin) influence on oxidative stress parameters such as concentrations of malondialdehyde (MDA), hydrogen peroxide (H2O2), glutathione, and free sulfhydryl groups content. Experiments were carried out on healthy volunteers (). The subjects were divided into women group () and men group () and randomly assigned to synbiotic and control groups. Blood samples were collected before synbiotic supplementation and after 7 wks, at the end of the study. The administration of synbiotic resulted in a significant decrease in MDA (), H2O2 (), and GSSG concentrations () as compared with the control groups and significant increase in the concentrations of GSHt (), GSH (), and -SH group content () versus control. Synbiotics containing L. casei plus inulin may have positive influence on selected oxidative stress markers.