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Oxidative Medicine and Cellular Longevity
Volume 2018, Article ID 3246719, 11 pages
https://doi.org/10.1155/2018/3246719
Research Article

Antioxidant Activity and Genotoxic Assessment of Crabwood (Andiroba, Carapa guianensis Aublet) Seed Oils

1Environmental Mutagenesis Laboratory, Department of Biophysics and Biometry, Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil
2Genotoxicity Laboratory, Department of Genetics and Molecular Biology, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil
3Integrated Laboratory of Plant Biology, Department of Botany, Institute of Biosciences, Federal University of State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
4Embrapa Food Technology, Brasília, DF, Brazil

Correspondence should be addressed to Israel Felzenszwalb; moc.liamg@nezlef.jreu

Received 13 December 2017; Revised 22 February 2018; Accepted 3 April 2018; Published 2 May 2018

Academic Editor: Jaideep Banerjee

Copyright © 2018 Carlos F. Araujo-Lima et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. H. Costa-Silva, C. R. Lima, E. J. R. Silva et al., “Acute and subacute toxicity of the Carapa guianensis Aublet (Meliaceae) seed oil,” Journal of Ethnopharmacology, vol. 116, no. 3, pp. 495–500, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Henriques and C. Penido, “The therapeutic properties of Carapa guianensis,” Current Pharmaceutical Design, vol. 20, no. 6, pp. 850–856, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Penido, K. A. Costa, R. J. Pennaforte et al., “Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia,” Inflammation Research, vol. 54, no. 7, pp. 295–303, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Penido, F. P. Conte, M. S. S. Chagas, C. A. B. Rodrigues, J. F. G. Pereira, and M. G. M. O. Henriques, “Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice,” Inflammation Research, vol. 55, no. 11, pp. 457–464, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. C. M. Cazal, K. Choosang, V. G. P. Severino et al., “Evaluation of effect of triterpenes and limonoids on cell growth, cell cycle and apoptosis in human tumor cell line,” Anti-Cancer Agents in Medicinal Chemistry, vol. 10, no. 10, pp. 769–776, 2010. View at Publisher · View at Google Scholar
  6. F. N. de Barros, M. P. O. Farias, J. P. C. Tavares, L. C. Alves, and M. A. d. G. Faustino, “In vitro efficacy of oil from the seed of Carapa guianensis (andiroba) in the control of Felicola subrostratus,” Revista Brasileira de Farmacognosia, vol. 22, no. 5, pp. 1130–1133, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. C. E. S. Silva, O. J. dos Santos, J. M. Ribas-Filho et al., “Effect of Carapa guianensis Aublet (andiroba) and Orbignya phalerata (babassu) in colonic healing in rats,” Revista do Colégio Brasileiro de Cirurgiões, vol. 42, no. 6, pp. 399–406, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. H. A. Miot, R. F. Batistella, K. d. A. Batista et al., “Comparative study of the topical effectiveness of the andiroba oil (Carapa guianensis) and DEET 50% as repellent for Aedes sp,” Revista do Instituto de Medicina Tropical de São Paulo, vol. 46, no. 5, pp. 253–256, 2004. View at Publisher · View at Google Scholar
  9. F. A. C. de Mendonça, K. F. S. da Silva, K. K. dos Santos, K. A. L. Ribeiro Júnior, and A. E. G. Sant'Ana, “Activities of some Brazilian plants against larvae of the mosquito Aedes aegypti,” Fitoterapia, vol. 76, no. 7-8, pp. 629–636, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. M. P. O. Farias, D. P. Sousa, A. C. Arruda et al., “Potencial acaricida do óleo de andiroba Carapa guianensis Aubl. sobre fêmeas adultas ingurgitadas de Anocentor nitens Neumann, 1897 e Rhipicephalus sanguineus Latreille, 1806,” Arquivo Brasileiro de Medicina Veterinária e Zootecnia, vol. 61, no. 4, pp. 877–882, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. C. O. Carvalho, A. C. S. Chagas, F. Cotinguiba et al., “The anthelmintic effect of plant extracts on Haemonchus contortus and Strongyloides venezuelensis,” Veterinary Parasitology, vol. 183, no. 3-4, pp. 260–268, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Shanley and M. Londres, “Andiroba Carapa guianensis Aubl,” in Fruit Trees and Useful Plants in Amazonian Life. Trees and Vines, P. Shanley et al., Ed., Food and Agriculture Organization of the United Nations (FAO), 2011, http://www.fao.org/docrep/015/i2360e/i2360e03.pdf. View at Google Scholar
  13. M. Nardi, A. C. Lira-Guedes, H. F. Albuquerque Cunha, M. C. Guedes, K. Mustin, and S. C. P. Gomes, “Artisanal extraction and traditional knowledge associated with medicinal use of crabwood oil (Carapa guianensis Aublet.) in a Peri-Urban Várzea environment in the Amazon estuary,” Evidence-based Complementary and Alternative Medicine, vol. 2016, Article ID 5828021, 12 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. C. R. Souza, R. M. B. Lima, C. P. Azevedo, and L. M. B. Ross, Andiroba (Carapa guianensis Aubl), Embrapa Amazônia Ocidental, Manaus, Brazil, 2006, (Embrapa Amazônia Ocidental. Documentos, 48).
  15. V. P. da Silva, R. R. Oliveira, and M. R. Figueiredo, “Isolation of limonoids from seeds of Carapa guianensis Aublet (Meliaceae) by high-speed countercurrent chromatography,” Phytochemical Analysis, vol. 20, no. 1, pp. 77–81, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. F. D. Gunstone, “Vegetable Oils,” in Bailey's Industrial Oils and Fats, F. Shahidi, Ed., pp. 213–267, John Wiley & Sons Ltd., Chichester, UK, 6th edition, 2005. View at Google Scholar
  17. H. R. Bizzo and R. Antoniassi, “Fixed oils and antimicrobial effects,” in Recent Progress in Medicinal Plants Vol. 33 Fixed Oils and Fats, J. N. Govil, Ed., pp. 273–285, Studium Press, England and Wales, 2012. View at Google Scholar
  18. “Guidance document on revisions to OECD genetic toxicology test guidelines,” OECD, Paris, France, Genetic toxicology Guidance Document, August 2015.
  19. K. Mortelmans and E. Zeiger, “The Ames Salmonella/microsome mutagenicity assay,” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 455, no. 1-2, pp. 29–60, 2000. View at Publisher · View at Google Scholar · View at Scopus
  20. L. Hartman and R. C. Lago, “Rapid preparation of fatty acid methyl esters from lipids,” Laboratory Practice, vol. 22, no. 6, pp. 475–6 passim, 1973. View at Google Scholar
  21. AOCS, “Official methods and recommended practices of the AOCS,” 2009, http://agris.fao.org/agris-search/search.do?recordID=US201300136250.
  22. X. Liu and T. Osawa, “cis Astaxanthin and especially 9-cis astaxanthin exhibits a higher antioxidant activity in vitro compared to the all-trans isomer,” Biochemical and Biophysical Research Communications, vol. 357, no. 1, pp. 187–193, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. A. S. Fernandes, J. L. Mazzei, C. G. Oliveira et al., “Protection against UV-induced toxicity and lack of mutagenicity of Antarctic Sanionia uncinata,” Toxicology, vol. 376, pp. 126–136, 2017. View at Publisher · View at Google Scholar · View at Scopus
  24. C. F. Araujo-Lima, R. J. M. Nunes, R. M. Carpes, C. A. F. Aiub, and I. Felzenszwalb, “Pharmacokinetic and toxicological evaluation of a zinc gluconate-based chemical sterilant using in vitro and in silico approaches,” BioMed Research International, vol. 2017, Article ID 5746768, 8 pages, 2017. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Boechat, A. S. Carvalho, K. Salomão et al., “Studies of genotoxicity and mutagenicity of nitroimidazoles: demystifying this critical relationship with the nitro group,” Memórias do Instituto Oswaldo Cruz, vol. 110, no. 4, pp. 492–499, 2015. View at Publisher · View at Google Scholar · View at Scopus
  26. F. S. Cardoso, C. F. Araujo-Lima, C. A. F. Aiub, and I. Felzenszwalb, “Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring,” Toxicology Letters, vol. 260, pp. 36–45, 2016. View at Publisher · View at Google Scholar · View at Scopus
  27. E. R. A. Ferraz, C. R. Rainho, A. S. Fernandes, and I. Felzenszwalb, “Differential toxicity of an organic PM2.5 extract to human lung cells cultured in three dimensions (3D) and monolayers,” Journal of Toxicology and Environmental Health, Part A, vol. 79, no. 5, pp. 221–231, 2016. View at Publisher · View at Google Scholar · View at Scopus
  28. I. Felzenszwalb, M. R. da Costa Marques, J. L. Mazzei, and C. A. F. Aiub, “Toxicological evaluation of Euterpe edulis: a potential superfruit to be considered,” Food and Chemical Toxicology, vol. 58, pp. 536–544, 2013. View at Publisher · View at Google Scholar · View at Scopus
  29. R. C. Dutra, M. M. Campos, A. R. S. Santos, and J. B. Calixto, “Medicinal plants in Brazil: pharmacological studies, drug discovery, challenges and perspectives,” Pharmacological Research, vol. 112, pp. 4–29, 2016. View at Publisher · View at Google Scholar · View at Scopus
  30. R. Ananthi, N. Chandra, S. T. Santhiya, and A. Ramesh, “Genotoxic and antigenotoxic effects of Hemidesmus indicus R. Br. root extract in cultured lymphocytes,” Journal of Ethnopharmacology, vol. 127, no. 2, pp. 558–560, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. P. R. Melo-Reis, L. S. Bezerra, M. A. Vale, R. F. Canhête, and L. Chen-Chen, “Assessment of the mutagenic and antimutagenic activity of Synadenium umbellatum Pax latex by micronucleus test in mice,” Brazilian Journal of Biology, vol. 71, no. 1, pp. 169–174, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. G. G. Regner, J. Gianesini, R. G. von Borowski et al., “Toxicological evaluation of Pterocaulon polystachyum extract: a medicinal plant with antifungal activity,” Environmental Toxicology and Pharmacology, vol. 31, no. 1, pp. 242–249, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. G. Sponchiado, M. L. Adam, C. D. Silva et al., “Quantitative genotoxicity assays for analysis of medicinal plants: a systematic review,” Journal of Ethnopharmacology, vol. 178, pp. 289–296, 2016. View at Publisher · View at Google Scholar · View at Scopus
  34. J. H. Costa-Silva, M. M. A. Lyra, C. R. Lima et al., “A toxicological evaluation of the effect of Carapa guianensis Aublet on pregnancy in Wistar rats,” Journal of Ethnopharmacology, vol. 112, no. 1, pp. 122–126, 2007. View at Publisher · View at Google Scholar · View at Scopus
  35. Q. Shuhua, W. Dagang, M. Yunbao, and L. Xiaodong, “A novel flavane from Carapa guianensis,” Acta Botanica Sinica, vol. 45, no. 9, pp. 1129–1133, 2003. View at Google Scholar
  36. A. Ammouche, F. Rouaki, A. Bitam, and M. M. Bellal, “Effect of ingestion of thermally oxidized sunflower oil on the fatty acid composition and antioxidant enzymes of rat liver and brain in development,” Annals of Nutrition & Metabolism, vol. 46, no. 6, pp. 268–275, 2002. View at Publisher · View at Google Scholar · View at Scopus
  37. N. Totani, S. Tateishi, T. Mori, and E. G. Hammond, “Oxidation of frying oils during intermittent usage,” Journal of Oleo Science, vol. 61, no. 11, pp. 601–607, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. I. Felzenszwalb, J. L. da Costa Mazzei, S. Feitosa, C. A. Fortes Aiub, and D. T. de Almeida, “Toxicological assessment of crude palm oil (Elaeis guineensis Jacq.) used in deep frying of akara (cowpea paste finger food),” Grasas y Aceites, vol. 65, no. 2, article e020, 2014. View at Publisher · View at Google Scholar · View at Scopus
  39. B. Qi, Q. Zhang, X. Sui, Z. Wang, Y. Li, and L. Jiang, “Differential scanning calorimetry study—assessing the influence of composition of vegetable oils on oxidation,” Food Chemistry, vol. 194, pp. 601–607, 2016. View at Publisher · View at Google Scholar · View at Scopus
  40. C. E. Richardson, M. Hennebelle, Y. Otoki et al., “Lipidomic analysis of oxidized fatty acids in plant and algae oils,” Journal of Agricultural and Food Chemistry, vol. 65, no. 9, pp. 1941–1951, 2017. View at Publisher · View at Google Scholar · View at Scopus
  41. S. S. R. Milhomem-Paixão, M. L. Fascineli, M. M. Roll et al., “The lipidome, genotoxicity, hematotoxicity and antioxidant properties of andiroba oil from the Brazilian Amazon,” Genetics and Molecular Biology, vol. 39, no. 2, pp. 248–256, 2016. View at Publisher · View at Google Scholar · View at Scopus
  42. A. R. P. Ambrozin, A. C. Leite, F. C. Bueno et al., “Limonoids from andiroba oil and Cedrela fissilis and their insecticidal activity,” Journal of the Brazilian Chemical Society, vol. 17, no. 3, 2006. View at Publisher · View at Google Scholar
  43. B. S. Nayak, J. Kanhai, D. M. Milne et al., “Investigation of the wound healing activity of Carapa guianensis L. (Meliaceae) bark extract in rats using excision, incision, and dead space wound models,” Journal of Medicinal Food, vol. 13, no. 5, pp. 1141–1146, 2010. View at Publisher · View at Google Scholar
  44. R. N. C. Miranda Júnior, M. F. Dolabela, M. N. da Silva, M. M. Póvoa, and J. G. S. Maia, “Antiplasmodial activity of the andiroba (Carapa guianensis Aubl., Meliaceae) oil and its limonoid-rich fraction,” Journal of Ethnopharmacology, vol. 142, no. 3, pp. 679–683, 2012. View at Publisher · View at Google Scholar · View at Scopus
  45. P. Ngamwongsatit, P. P. Banada, W. Panbangred, and A. K. Bhunia, “WST-1-based cell cytotoxicity assay as a substitute for MTT-based assay for rapid detection of toxigenic Bacillus species using CHO cell line,” Journal of Microbiological Methods, vol. 73, no. 3, pp. 211–215, 2008. View at Publisher · View at Google Scholar · View at Scopus
  46. C. A. Patwardhan, A. Fauq, L. B. Peterson, C. Miller, B. S. J. Blagg, and A. Chadli, “Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis,” Journal of Biological Chemistry, vol. 288, no. 10, pp. 7313–7325, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. M. Llana-Ruiz-Cabello, S. Pichardo, S. Maisanaba et al., “In vitro toxicological evaluation of essential oils and their main compounds used in active food packaging: a review,” Food and Chemical Toxicology, vol. 81, pp. 9–27, 2015. View at Publisher · View at Google Scholar · View at Scopus