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Oxidative Medicine and Cellular Longevity
Volume 2018 (2018), Article ID 3537609, 15 pages
https://doi.org/10.1155/2018/3537609
Research Article

A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS

1Department of Cardiology & National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing 100853, China
2Department of Cardiology, Chengdu Military General Hospital, Chengdu 610083, China
3Department of Toxicology, School of Public Health, Fourth Military Medical University, Xi’an, Shaanxi 710032, China
4Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi 710032, China
5Institute of Burn Research, State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University, Chongqing 400038, China

Correspondence should be addressed to Feng Cao; moc.361@8288oacgnef

Received 30 July 2017; Revised 2 November 2017; Accepted 4 December 2017; Published 13 February 2018

Academic Editor: Nabil Eid

Copyright © 2018 Shuang Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Shuang Li, Hao Wu, Dong Han, et al., “A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS,” Oxidative Medicine and Cellular Longevity, vol. 2018, Article ID 3537609, 15 pages, 2018. doi:10.1155/2018/3537609