Relation of Redox and Structural Alterations of Rat Skin in the Function of Chronological Aging
Expression of methionine sulfoxide reductase A (MsrA) in the skin of 3-day-, 15-day-, 1-month-, 3-month-, 6-month-, and 21-month-old rats. Tissues were subjected to immunohistochemistry using an MsrA-specific antibody. The brown staining testifies to the specific reaction. The quantitative evaluation of MsrA antibody staining intensity in skin sections (b) was analyzed as described in Figure 3. The relative mean intensity was determined from 6 images for each aging group (). Data were presented as In respect to 3-month-old rats; . Representative slides are shown at ×40 magnification, orig.