Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway
ROS regulated the activities of ABL1, inflammation, proliferation, migration, and EMT of GC cell lines. (a) H2O2 led to the alteration of ABL1 and inflammation factors in GC cell lines and EMT markers in GC cells. (b and c) H2O2 promoted the proliferation and migration of GC cells. (d) H2O2 induced the EMT of GC cells.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.