Sodium Butyrate-Modulated Mitochondrial Function in High-Insulin Induced HepG2 Cell Dysfunction
AKT and AMPK signaling pathways participated in effects of NaB on mitochondria. Expression and activation of (a, b) p-AKT/AKT, (c, d) p-GSK3/GSK3, (e–g) p-AMPK/AMPK, and (h, i) PGC1-α were observed by immunofluorescence method (magnification: 800). NC: normal control; IR: high insulin-induced insulin resistance; NaB: sodium butyrate. ,, and .
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