Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway

Figure 6

SHTL decreased progression of atherosclerotic plaque and regulated PPAR-γ/LXR-α/ABAC1 expression in ApoE^-/- mice. (a) Representative images of Oil red O staining of en face preparations of aortas and the quantification of the atherosclerotic surface area of the entire aorta (, ). (b, c) Representative images and the quantification of aorta sections stained with Oil red O (, , ). (d) Positive expression of PPAR-γ, LXR-α, and ABCA1 in aorta sections detected by immunohistochemical staining. Representative images with 80x and 400x are shown. (, , ). versus the HFD group.

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