Acrocomia aculeata (Jacq.) Lodd. ex Mart. Leaves Increase SIRT1 Levels and Improve Stress Resistance

Figure 4

Inhibition of ROS generation by EA-Aa in Cos-7 cells. (a) Viability of Cos-7 cells treated with EA-Aa (500-1,000 μg·mL^-1) incubated with or without H₂O₂ (0.5 μM), shows low cytotoxicity of EA-Aa and protection (750–1,000 μg·mL^-1) against H₂O₂-induced oxidative damage from the decrease of H₂O₂-induced ROS (stained with DCF) (b) and O₂^⋅- generation (stained with DHE) (c) with EA-Aa (500–1,000 μg·mL^-1). Representative images of DCF and DHE are shown in (d) and (e), respectively. vs. control; vs. H₂O₂; ^#; ^##; .

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