Oxidative Medicine and Cellular Longevity

Redox Signaling and Neural Control of Cardiovascular Function


Status
Published

Lead Editor

1University of Nebraska Medical Center, Nebraska, USA

2UT Southwestern Medical Center, Texas, USA

3Wayne State, Michigan, USA

4Second Military Medical University, Shanghai, China


Redox Signaling and Neural Control of Cardiovascular Function

Description

Endogenous redox signaling molecules such as reactive oxygen species (ROS), nitric oxide (NO), and hydrogen sulfide (H2S) have been widely reported to be involved in modulating cardiovascular activity under normal physiological conditions. Additionally, growing evidence from basic and clinical studies also suggests a probable role of redox imbalance as a potential causal mechanism in many cardiovascular diseases such as aging, heart failure, hypertension, and peripheral arterial disease. Elucidation of these mechanisms has led to the development of successful therapies, novel tools to characterize these clinical conditions, and enhancement of patient care.

We invite authors to submit original research and review articles that support the continuing efforts to 1) identify novel redox signaling pathways underlying cardiovascular diseases and 2) discover original therapeutic strategies to treat these conditions and the evaluation of outcomes. We are particularly interested in articles clarifying how redox molecules are involved in neural reflex control of cardiovascular activity under physiological and pathological conditions. Another particular interest of this issue will be focused on a role of redox signaling in mediating cardiovascular adaption to acute and long term exercise both in health and disease.

Potential topics include, but are not limited to:

  • Redox biology in the autonomic nervous system in health and cardiovascular diseases
  • Central nervous system redox signaling and abnormal cardiovascular reflexes in cardiovascular diseases such as heart failure, hypertension, aging, and peripheral arterial diseases
  • Redox signaling and peripheral afferent sensitization/desensitization
  • Redox signaling and ion channel dysfunction in central and peripheral nervous system
  • Redox signaling and cardiovascular adaption to acute and/or long-term exercise in cardiovascular diseases
  • Redox signaling and cardiac remodeling in cardiomyopathy, hypertension, and heart failure
  • Redox signaling in the immune system in cardiovascular diseases such as heart failure, hypertension, aging, and peripheral arterial diseases
  • Redox mechanisms involved with central, peripheral, and/or autonomic nervous system regulation of the immune system in health and cardiovascular disease
  • Functional and redox changes in the immune system as a result of acute and/or long-term exercise in health and cardiovascular diseases
  • Antioxidant therapy and autonomic dysfunction in cardiovascular diseases
  • New and/or emerging therapies to treat abnormal redox signaling in cardiovascular disease

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 7086018
  • - Editorial

Redox Signaling and Neural Control of Cardiovascular Function

Hanjun Wang | Adam J. Case | ... | Scott A. Smith
  • Special Issue
  • - Volume 2016
  • - Article ID 5868913
  • - Research Article

Exercise Training Attenuates Upregulation of p47phox and p67phox in Hearts of Diabetic Rats

Neeru M. Sharma | Brandon Rabeler | ... | Kaushik P. Patel
  • Special Issue
  • - Volume 2016
  • - Article ID 3959087
  • - Research Article

Angiotensin II-Induced Hypertension Is Attenuated by Overexpressing Copper/Zinc Superoxide Dismutase in the Brain Organum Vasculosum of the Lamina Terminalis

John P. Collister | Heather Taylor-Smith | ... | Matthew C. Zimmerman
  • Special Issue
  • - Volume 2016
  • - Article ID 7413963
  • - Research Article

Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats

Chang-zhen Ren | Ya-Hong Yang | ... | Yang-Kai Wang
  • Special Issue
  • - Volume 2016
  • - Article ID 1451676
  • - Research Article

Inhibition of Receptor Interacting Protein Kinases Attenuates Cardiomyocyte Hypertrophy Induced by Palmitic Acid

Mingyue Zhao | Lihui Lu | ... | Xiaojing Liu
  • Special Issue
  • - Volume 2016
  • - Article ID 3686829
  • - Research Article

SOD1 Overexpression Preserves Baroreflex Control of Heart Rate with an Increase of Aortic Depressor Nerve Function

Jeffrey Hatcher | He Gu | Zixi (Jack) Cheng
  • Special Issue
  • - Volume 2016
  • - Article ID 9802136
  • - Research Article

Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation

Esteban A. Moya | Paulina Arias | ... | Rodrigo Iturriaga
  • Special Issue
  • - Volume 2016
  • - Article ID 3981790
  • - Research Article

Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats

Shu-Yan Dai | Yu-Ping Zhang | ... | Jing-Jing He
  • Special Issue
  • - Volume 2016
  • - Article ID 5843672
  • - Research Article

Morin Attenuates Ovalbumin-Induced Airway Inflammation by Modulating Oxidative Stress-Responsive MAPK Signaling

Yuan Ma | Ai Ge | ... | Mao Huang
  • Special Issue
  • - Volume 2016
  • - Article ID 7263736
  • - Research Article

HDAC6 Regulates the Chaperone-Mediated Autophagy to Prevent Oxidative Damage in Injured Neurons after Experimental Spinal Cord Injury

Min Su | Huaqing Guan | ... | Weixin Yang
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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