Oxidative Medicine and Cellular Longevity

Oxidative Stress and Inflammation in Cardiovascular Disease


Publishing date
07 Apr 2017
Status
Published
Submission deadline
18 Nov 2016

Lead Editor

1Tecnológico de Monterrey, Monterrey, Mexico

2Instituto Nacional de Cardiología-Ignacio Chávez, Mexico City, Mexico

3University of Texas Medical Branch, Galveston, USA


Oxidative Stress and Inflammation in Cardiovascular Disease

Description

Free radicals such as reactive oxygen and nitrogen species (ROS and RNS) are produced physiologically by various biochemical pathways and regulate numerous signaling processes and cellular homeostasis. However, under pathological conditions, loss of antioxidant defense creates an imbalance in the redox cellular environment leading to diverse disorders and augments the proinflammatory response.

Oxidative nitrosative stress and inflammation occurring in metabolic disorders such as obesity, hypertension, and diabetes have been postulated as underlying mechanisms of cardiovascular diseases development. Evidences from experimental and clinical studies have shown that left ventricular hypertrophy, fibrosis, diastolic dysfunction, heart failure, and ischemia/reperfusion damage are some of the pathologies related to deregulation of the mechanisms that control oxidative nitrosative stress and inflammation.

In this special issue, we are inviting researchers to contribute original research as well as review articles in this field, to broaden our understanding of the link between oxidative/ nitrosative stress and inflammation processes in cardiovascular diseases.

Potential topics include, but are not limited to:

  • Oxidative stress and inflammation in cardiac hypertrophy
  • Oxidative stress and inflammation in cardiac fibrosis
  • Role of oxidative stress and inflammation in heart failure
  • Role of mitochondria as main ROS generators in cardiovascular diseases
  • Relationship between oxidative stress and inflammation in cardiovascular diseases
  • Metabolic changes in cardiovascular diseases related to oxidative stress
  • Novel antioxidant and anti-inflammatory-based therapies in cardiovascular disease

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 5853238
  • - Editorial

Oxidative Stress and Inflammation in Cardiovascular Disease

Noemí García | Cecilia Zazueta | Leopoldo Aguilera-Aguirre
  • Special Issue
  • - Volume 2017
  • - Article ID 4157213
  • - Research Article

Role of Protein Kinase C and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide

Judith Stein | Sebastian Steven | ... | Andreas Daiber
  • Special Issue
  • - Volume 2017
  • - Article ID 3671751
  • - Research Article

Prevention of Streptozotocin-Induced Diabetic Nephropathy by MG132: Possible Roles of Nrf2 and IκB

Lili Kong | Yangwei Wang | ... | Lining Miao
  • Special Issue
  • - Volume 2017
  • - Article ID 5750897
  • - Research Article

Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload

Yuriana Oropeza-Almazán | Eduardo Vázquez-Garza | ... | Gerardo García-Rivas
  • Special Issue
  • - Volume 2017
  • - Article ID 6838921
  • - Research Article

Identification of Patients Affected by Mitral Valve Prolapse with Severe Regurgitation: A Multivariable Regression Model

Paola Songia | Benedetta Porro | ... | Paolo Poggio
  • Special Issue
  • - Volume 2016
  • - Article ID 9045736
  • - Research Article

Demethoxycurcumin Preserves Renovascular Function by Downregulating COX-2 Expression in Hypertension

Yingjuan Li | Danyang Tian | ... | Liqun Ren
  • Special Issue
  • - Volume 2016
  • - Article ID 5271251
  • - Research Article

Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways

Raffaella Mastrocola | Claudia Penna | ... | Massimo Collino
  • Special Issue
  • - Volume 2016
  • - Article ID 3128280
  • - Research Article

Lycopene Ameliorates Transplant Arteriosclerosis in Vascular Allograft Transplantation by Regulating the NO/cGMP Pathways and Rho-Associated Kinases Expression

Yunqiang He | Peng Xia | ... | Ziqiang Xu
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision74 days
Acceptance to publication36 days
CiteScore4.520
Impact Factor4.868
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