Oxidative Medicine and Cellular Longevity

Oxidative Stress and Trauma Repair


Publishing date
01 Feb 2022
Status
Closed
Submission deadline
24 Sep 2021

Lead Editor
Guest Editors

1Wenzhou University, Wenzhou, China

2Sun Yat-sen University, Guangzhou, China

3Cedars-Sinai Medical Center, Los Angeles, USA

This issue is now closed for submissions.
More articles will be published in the near future.

Oxidative Stress and Trauma Repair

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Trauma repair is a complex process involving multiple pathophysiological mechanisms, in which oxidative stress is one of the important mechanisms. Oxidative stress occurs at the beginning of trauma and accompanies the whole process of trauma repair. Excessive oxidative stress causes damage to lipids, proteins, and DNA, leading to cell necrosis and apoptosis, thus affecting trauma repair.

Trauma repair includes three processes: inflammatory response, cell proliferation, and tissue remodeling. Various mediators and growth factors are involved in this process. The factors that interfere with the regulation of trauma repair can hinder the process of trauma repair. Recently, the research directions of trauma have mainly focused on the four aspects: the mechanism of occurrence and prevention of systemic damage; repair and regeneration of tissue injury, with a focus on the molecular mechanism of trauma repair of important tissues (skin, lung, bone, nerve, etc.) and stem cells in tissue repair; the key technologies and transformation of treatment of major injuries; and the development of trauma rescue equipment and new drugs in the treatment of trauma. The study of the molecular mechanism of trauma repair is essential for drug development and strategy selection. In the past 15 years, the research of trauma repair has gradually changed from the pursuit of healing speed to the quality of healing and has paid more attention to functional recovery and tissue reconstruction.

This Special Issue will focus on the research of the regulatory role of oxidative stress in the process of trauma repair. It is hoped that the research of this Special Issue will improve the regulatory theoretical system of trauma repair, and provide more targets related to oxidative stress. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

  • The regulatory role of oxidative stress in spinal cord injury
  • The regulatory effect of oxidative stress in peripheral nerve injury
  • The regulatory molecular mechanism of oxidative stress during traumatic brain injury recovery
  • Therapeutic effect of antioxidants on nerve injury repair
  • The effect of oxidative stress on wound repair
  • Therapeutic effect of antioxidants on wound repair

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 2076680
  • - Review Article

Silk Fibroin Hydrogels Could Be Therapeutic Biomaterials for Neurological Diseases

Chun Yang | Sunao Li | ... | Mingyang Zhang
  • Special Issue
  • - Volume 2022
  • - Article ID 1015791
  • - Review Article

Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals

An-Guo Wu | Yuan-Yuan Yong | ... | Da-Lian Qin
  • Special Issue
  • - Volume 2022
  • - Article ID 1623181
  • - Review Article

Microtubule Organization Is Essential for Maintaining Cellular Morphology and Function

Lijiang Huang | Yan Peng | ... | Wei Zuo
  • Special Issue
  • - Volume 2022
  • - Article ID 8010670
  • - Research Article

Sesamol Attenuates Neuroinflammation by Regulating the AMPK/SIRT1/NF-κB Signaling Pathway after Spinal Cord Injury in Mice

Xiaochu Feng | Xianghang Chen | ... | Keyong Ye
  • Special Issue
  • - Volume 2022
  • - Article ID 3235524
  • - Review Article

Role of NETosis in Central Nervous System Injury

Yituo Chen | Haojie Zhang | ... | Kailiang Zhou
  • Special Issue
  • - Volume 2021
  • - Article ID 4280951
  • - Research Article

Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation

Tao Chen | Xiao Qian | ... | Yu-Hai Wang
  • Special Issue
  • - Volume 2021
  • - Article ID 6114132
  • - Review Article

Contribution of Oxidative Stress to HIF-1-Mediated Profibrotic Changes during the Kidney Damage

Hong Zhang | Renfeng Xu | Zhengchao Wang
  • Special Issue
  • - Volume 2021
  • - Article ID 8186877
  • - Research Article

GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation

Yu Xu | Xinli Hu | ... | Hui Xu
  • Special Issue
  • - Volume 2021
  • - Article ID 3846122
  • - Review Article

Effects of Exercise-Induced ROS on the Pathophysiological Functions of Skeletal Muscle

Fan Wang | Xin Wang | ... | Zhenghong Zhang
  • Special Issue
  • - Volume 2021
  • - Article ID 1764929
  • - Research Article

HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats

Zonghao Tang | Jiajie Chen | ... | Zhengchao Wang
Oxidative Medicine and Cellular Longevity
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.