Oxidative Medicine and Cellular Longevity

Aging, Metabolic, and Degenerative Disorders: Biomedical Value of Antioxidants


Status
Published

1Suez Canal University, Ismailia, Egypt

2National Cancer Institute, Cairo, Egypt

3Bourgogne Franche-Comté University, Besançon, France

4University of Oradea, Oradea, Romania

5D. Y. Patil University, Kolhapur, India

6King Saud University, Riyadh, Saudi Arabia


Aging, Metabolic, and Degenerative Disorders: Biomedical Value of Antioxidants

Description

Oxidative stress plays an important role in the pathogenesis of aging as well as different metabolic and degenerative diseases. Excess free radicals production is incriminated in the pathogenesis of various metabolic disorders, including diabetes, obesity, and atherosclerosis. Many degenerative diseases such as cancer, hypertension, Alzheimer’s, and Parkinsonism, inflammatory bowel disease, and rheumatoid arthritis are characterized by imbalance between oxidant and antioxidant system in the body. Cellular aging as well as various metabolic and degenerative disorders could be developed under laboratory conditions as models induced by certain chemicals and drug toxicities with reactive oxygen species production as a mechanism.

Antioxidants are efficient redox active radical scavenging agents, due to their ability to reduce oxidative damage in living cells. Moreover, they played a fundamental role in human and animals’ life and health, owing to their substantial benefits of biomedical applications, including metabolic and degenerative disease prevention and treatment as well as food supplementation against aging process.

This special issue is dedicated to integrating the previous and the current biomedical and molecular mechanisms of antioxidants in preventing and treating oxidative stress and associated metabolic and degenerative diseases. We cordially invite scientists and researchers to contribute their basic and clinical studies via original and review articles in our special issue.

Potential topics include but are not limited to the following:

  • Antioxidant as a food supplement for aging process
  • Implication of antioxidant for metabolic disorders
  • Application of antioxidant for prevention and treatment of degenerative diseases
  • Potential redox biomarkers of aging and metabolic and degenerative diseases
  • Antioxidant toxicity in relation to aging metabolic disorders and degenerative diseases
  • Novel antioxidants and their molecular mechanisms of action

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 2098123
  • - Editorial

Aging, Metabolic, and Degenerative Disorders: Biomedical Value of Antioxidants

Mohamed M. Abdel-Daim | Nadia I. Zakhary | ... | Nikhat J. Siddiqi
  • Special Issue
  • - Volume 2018
  • - Article ID 8753063
  • - Research Article

Longevity-Related Gene Transcriptomic Signature in Glioblastoma Multiforme

Manal S. Fawzy | Dahlia I. Badran | ... | Eman A. Toraih
  • Special Issue
  • - Volume 2018
  • - Article ID 3250864
  • - Review Article

Mesenchymal Stromal Cell Therapy for Pancreatitis: A Systematic Review

Sara M. Ahmed | Mahmoud Morsi | ... | Nagwa El-Badri
  • Special Issue
  • - Volume 2018
  • - Article ID 8104165
  • - Research Article

Black Seed Thymoquinone Improved Insulin Secretion, Hepatic Glycogen Storage, and Oxidative Stress in Streptozotocin-Induced Diabetic Male Wistar Rats

Heba M. A. Abdelrazek | Omnia E. Kilany | ... | Aaser M. Abdelazim
  • Special Issue
  • - Volume 2018
  • - Article ID 5106469
  • - Research Article

Rutin Isolated from Chrozophora tinctoria Enhances Bone Cell Proliferation and Ossification Markers

Ashraf B. Abdel-Naim | Abdullah A. Alghamdi | ... | Ali M. El-Halawany
  • Special Issue
  • - Volume 2017
  • - Article ID 6745840
  • - Research Article

Comparison of Selected Parameters of Redox Homeostasis in Patients with Ataxia-Telangiectasia and Nijmegen Breakage Syndrome

Barbara Pietrucha | Edyta Heropolitanska-Pliszka | ... | Bozena Mikoluc
  • Special Issue
  • - Volume 2017
  • - Article ID 3035184
  • - Research Article

Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes

Biruhalem Assefa | Ayman M. Mahmoud | ... | Ayman M. Arafat
  • Special Issue
  • - Volume 2017
  • - Article ID 8235069
  • - Research Article

Modulatory Effect of Fermented Papaya Extracts on Mammary Gland Hyperplasia Induced by Estrogen and Progestin in Female Rats

Zhenqiang You | Junying Sun | ... | Yanfei Xin
  • Special Issue
  • - Volume 2017
  • - Article ID 4824371
  • - Research Article

Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells

Tuzz-Ying Song | Nae-Cherng Yang | ... | Thuy Lan Vo Thi
  • Special Issue
  • - Volume 2017
  • - Article ID 3269379
  • - Research Article

MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma

Eman A. Toraih | Afaf T. Ibrahiem | ... | Aly A. M. Shaalan
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate42%
Submission to final decision56 days
Acceptance to publication39 days
CiteScore7.300
Impact Factor5.076
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