Optimizing a Rodent Model of Parkinson's Disease for Exploring the Effects and Mechanisms of Deep Brain Stimulation

Figure 3

COMSOL simulation. (a) Tissue layers and dimensions for the COMSOL calculation around a DBS electrode (radius: 100 μm; see Figure 8) in the STN of a rat brain using dimensions depicted in Figure 2. Tissues of similar dielectric properties are summarized by arrows. (b) COMSOL simulation of electric potential in the cross-section depicted in (a). For simplicity reasons, the values of gray matter at 130 Hz from Table 1 were used for the tissue assumed as “brain”.