Table of Contents Author Guidelines Submit a Manuscript
Parkinson’s Disease
Volume 2017, Article ID 2412486, 7 pages
https://doi.org/10.1155/2017/2412486
Research Article

LRRK2 G2019S Mutation: Prevalence and Clinical Features in Moroccans with Parkinson’s Disease

1Research Team in Neurology and Neurogenetics, Medical School and Pharmacy, Mohammed V University, Rabat, Morocco
2Department of Neurology and Neurogenetics, Specialties Hospital, Rabat, Morocco
3Laboratory of Public Health, Medical School and Pharmacy, Mohammed V University, Rabat, Morocco

Correspondence should be addressed to Ahmed Bouhouche; am.ten.s5mu@ehcuohuob.a

Received 9 December 2016; Accepted 23 March 2017; Published 30 March 2017

Academic Editor: Daniel Berwick

Copyright © 2017 Ahmed Bouhouche et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Genta Ito, and Taisuke Tomita, “Rab10 phosphorylation detection by LRRK2 activity using SDS-PAGE with a phosphate-binding tag,” Journal of Visualized Experiments, vol. 2017, no. 130, 2017. View at Publisher · View at Google Scholar
  • Ahmed Bouhouche, Christelle Tesson, Wafaa Regragui, Mounia Rahmani, Valérie Drouet, Houyam Tibar, Zouhayr Souirti, Rafiqua Ben El Haj, Naima Bouslam, Mohamed Yahyaoui, Alexis Brice, Ali Benomar, and Suzanne Lesage, “Mutation Analysis of Consanguineous Moroccan Patients with Parkinson’s Disease Combining Microarray and Gene Panel,” Frontiers in Neurology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Panchanan Maiti, Jayeeta Manna, and Gary L. Dunbar, “Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments,” Translational Neurodegeneration, vol. 6, no. 1, 2017. View at Publisher · View at Google Scholar
  • Rafiqua Ben El Haj, Ayyoub Salmi, Wafa Regragui, Ahmed Moussa, Naima Bouslam, Houyam Tibar, Ali Benomar, Mohamed Yahyaoui, and Ahmed Bouhouche, “Evidence for prehistoric origins of the G2019S mutation in the North African Berber population.,” PloS one, vol. 12, no. 7, 2017. View at Publisher · View at Google Scholar
  • Li Shu, Yuan Zhang, Hongxu Pan, Qian Xu, Jifeng Guo, Beisha Tang, and Qiying Sun, “Clinical Heterogeneity Among LRRK2 Variants in Parkinson's Disease: A Meta-Analysis,” Frontiers in Aging Neuroscience, vol. 10, 2018. View at Publisher · View at Google Scholar
  • Wei Di, Zhiyong Zeng, Jingyan Li, Xiaoling Liu, Minzhi Bo, and Hua Lv, “ The Association between LRRK2 G2385R and Phenotype of Parkinson’s Disease in Asian Population: A Meta-Analysis of Comparative Studies ,” Parkinson's Disease, vol. 2018, pp. 1–7, 2018. View at Publisher · View at Google Scholar
  • Noémie Cresto, Camille Gardier, Francesco Gubinelli, Marie-Claude Gaillard, Géraldine Liot, Andrew B. West, and Emmanuel Brouillet, “The unlikely partnership between LRRK2 and α-synuclein in Parkinson's disease,” European Journal of Neuroscience, 2018. View at Publisher · View at Google Scholar