Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease
Figure 2
Metabolites of daidzein. Daidzein is converted by anaerobic bacteria in the large intestine to several metabolites, dihydrodaidzein, O-desmethylangolensin, and equol. Each of these metabolites has a chiral center at C-3 due to the reduction of the Δ2-3 double bond (marked with a star*). Equol is found as its S-(-)-equol enantiomer. The chirality of the other daidzein metabolites is not known.
