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Volume 2012, Article ID 924256, 7 pages
Review Article

Structure Determination of a Natural Juvenile Hormone Isolated from a Heteropteran Insect

1Division of Insect Sciences, National Institute of Agrobiological Sciences, Ohwashi, Tsukuba, Ibaraki 305-8634, Japan
2Graduate School of Science, Osaka City University, Osaka 558-8585, Japan
3Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan

Received 15 September 2011; Accepted 7 November 2011

Academic Editor: Mark M. Feldlaufer

Copyright © 2012 Toyomi Kotaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Juvenile hormone (JH), which occurs in several forms in different insects, is one of the most important insect hormones. The structure of JH in Heteroptera has not been elucidated until recently, although insects in this suborder have long been used as experimental animals for JH research. Here we review the structure determination of a novel JH in a stink bug, Plautia stali, which was named juvenile hormone III skipped bisepoxide [JHSB3: methyl (2R,3S,10R)-2,3;10,11-bisepoxyfarnesoate], based on the arrangement of two epoxides at C2,3 and C10,11 with a skipped double bond at C6,7.