Review Article

Generation of Induced Pluripotent Stem (iPS) Cells by Nuclear Reprogramming

Table 2

Nuclear reprogramming factor delivery. List of reprogramming factors delivery by various methods shown in Table 2.

Mode of deliveryVectors

Viral deliveryMMLV retrovirus, lentivirus, adenovirus, hantavirus, transposon, retrotransposon.
Episomal deliveryPiggyBack, plasmid, minicircle, synthetic mRNA, IVT mRNA, protein, cell fusion (ES + adult), cell fusion (tumor + adult), protein delivery by gag protein,
Small molecule (chemical)ALK5 inhibitor, GSK3 inhibitor, and MEK inhibitor.