Semaphorin 3A Shifts Adipose Mesenchymal Stem Cells towards Osteogenic Phenotype and Promotes Bone Regeneration In Vivo

Figure 3

The fabrication of PLGA scaffolds engrafted with ASCs. (a) Schematic diagram of experiment procedure. (b) The morphology of PLGA scaffold-ASCs implants: (A) gross observation, (B) the lateral view of the scaffold without cells observed by SEM, (C) the surface view of the scaffold-ASCs implants under SEM, and (D) magnification to the inset in Figure 3(b)(C) and the cells were indicated by white arrow. (c) The critical size bone defect before (A) and after the transplantation of scaffold- ASCs implants (B).

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