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Stem Cells International
Volume 2017, Article ID 1609685, 13 pages
https://doi.org/10.1155/2017/1609685
Review Article

Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects

1Institute of Experimental Orthopaedics and Osteoarthritis Research, Saarland University, Kirrberger Strasse, Building 37, Homburg, 66421 Saar, Germany
2Department of Orthopaedic Surgery, Saarland University Medical Center, Kirrberger Strasse, Building 37, Homburg, 66421 Saar, Germany
3Institute for Clinical Haemostaseology and Transfusion Medicine, Saarland University, Kirrberger Strasse, Building 1/Building 57, Homburg, 66421 Saar, Germany

Correspondence should be addressed to Henning Madry; ue.sku@yrdam.gninneh

Received 29 January 2017; Revised 15 March 2017; Accepted 12 April 2017; Published 18 May 2017

Academic Editor: Mitsuo Ochi

Copyright © 2017 Henning Madry et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Liang Gao, Patrick Orth, Magali Cucchiarini, and Henning Madry, “ Effects of solid acellular type-I/III collagen biomaterials on in vitro and in vivo chondrogenesis of mesenchymal stem cells ,” Expert Review of Medical Devices, vol. 14, no. 9, pp. 717–732, 2017. View at Publisher · View at Google Scholar
  • Liang Gao, Patrick Orth, Magali Cucchiarini, and Henning Madry, “Autologous Matrix-Induced Chondrogenesis: A Systematic Review of the Clinical Evidence,” The American Journal of Sports Medicine, pp. 036354651774057, 2017. View at Publisher · View at Google Scholar
  • Shane A. Shapiro, Jennifer R. Arthurs, Michael G. Heckman, Joseph M. Bestic, Shari E. Kazmerchak, Nancy N. Diehl, Abba C. Zubair, and Mary I. O’Connor, “Quantitative T2 MRI Mapping and 12-Month Follow-up in a Randomized, Blinded, Placebo Controlled Trial of Bone Marrow Aspiration and Concentration for Osteoarthritis of the Knees,” Cartilage, pp. 194760351879614, 2018. View at Publisher · View at Google Scholar
  • Michael L. Redondo, Brian R. Waterman, Jack M. Bert, and Brian J. Cole, “Marrow Stimulation and Augmentation,” Cartilage Restoration, pp. 189–206, 2018. View at Publisher · View at Google Scholar
  • Tamás Oláh, and Henning Madry, “The Osteochondral Unit: The Importance of the Underlying Subchondral Bone,” Cartilage Restoration, pp. 13–22, 2018. View at Publisher · View at Google Scholar
  • Clayton W. Nuelle, and Jack Farr, “Internal Fixation of Osteochondritis Dissecans Lesions in the Patellofemoral Joint,” Journal of Knee Surgery, vol. 31, no. 3, pp. 206–211, 2018. View at Publisher · View at Google Scholar
  • Michael L. Redondo, Adam J. Beer, and Adam B. Yanke, “Cartilage Restoration: Microfracture and Osteochondral Autograft Transplantation,” Journal of Knee Surgery, vol. 31, no. 3, pp. 231–238, 2018. View at Publisher · View at Google Scholar
  • Hannah L. Holmes, Brooke Wilson, Julian P. Goerger, Jesse L. Silverberg, Itai Cohen, Warren R. Zipfel, and Lisa A. Fortier, “Facilitated recruitment of mesenchymal stromal cells by bone marrow concentrate and platelet rich plasma,” Plos One, vol. 13, no. 3, pp. e0194567, 2018. View at Publisher · View at Google Scholar
  • Ann-Kathrin Asen, Lars Goebel, Ana Rey-Rico, Jerome Sohier, David Zurakowski, Magali Cucchiarini, and Henning Madry, “Sustained spatiotemporal release of TGF-β1 confers enhanced very early chondrogenic differentiation during osteochondral repair in specific topographic patterns,” The FASEB Journal, vol. 32, no. 10, pp. 5298–5311, 2018. View at Publisher · View at Google Scholar