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Stem Cells International
Volume 2017, Article ID 2761678, 14 pages
Review Article

The Application of Stem Cells from Different Tissues to Cartilage Repair

1IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy
2Università Vita-Salute San Raffaele, Milan, Italy
3Department of Biomedical Sciences for Health, University of Milan, Milan, Italy

Correspondence should be addressed to Laura Mangiavini; ti.liamtoh@28namual

Received 31 May 2017; Accepted 24 October 2017; Published 10 December 2017

Academic Editor: Bernard A. J. Roelen

Copyright © 2017 James N. Fisher et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic level. Tissue engineering and regenerative medicine using stem/progenitor cells have emerged as valid alternatives to classical reparative techniques. This review offers a brief introduction and overview of the field, highlighting a number of tissue sources for stem/progenitor cell populations. Emphasis is given to recent developments in both clinical and basic sciences. The relative strengths and weaknesses of each tissue type are discussed.