Stem Cells International

Producing Stem Cell-Based Transplants for Future Therapeutic Purposes


Status
Published

Lead Editor

1National Autonomous University of Mexico, Mexico City, Mexico

2University of Edinburgh, Edinburgh, UK

3Pfizer - Universidad de Granada - Junta de Andalucía Centre for Genomics and Oncological Research, Granada, Spain


Producing Stem Cell-Based Transplants for Future Therapeutic Purposes

Description

Stem cell research holds the promise of developing new therapies for a wide range of human diseases. Different methods to direct stem cells to become differentiated cells have been reported, suggesting that they might be readily employed in regenerative medicine. However, such therapies will not reach extensive clinical application, unless each step of their development is assessed in disease-specific contexts. For this reason, only the use of proper models of disease will allow the correct evaluation of the outcomes of stem cell-based interventions.

Currently there is a great need for investigations that focus on matching a stem cells source with a specific application, the handling of stem cells to become therapeutically relevant, and improvements on the reproducibility of biological materials intended for therapy or evaluation of the risk/reward relationship on therapeutic interventions. We invite authors to contribute original research articles as well as timely reviews centered on the applicability of therapies involving stem cells in models relevant to human disease.

Potential topics include but are not limited to the following:

  • Induction, isolation, preservation, and/or expansion of stem cells with therapeutic purposes
  • Differentiation of stem cells as source of cellular therapies
  • Quality control and production reproducibility of cells intended for therapy
  • Bioengineering of stem cell-containing devices and methods for cell delivery
  • In vivo evaluation of efficacy and/or safety of stem cell-based therapies
  • Strategies to prevent tumor formation after grafting of stem cell progeny

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 9592302
  • - Editorial

Producing Stem Cell-Based Transplants for Future Therapeutic Purposes

Iván Velasco | Tilo Kunath | ... | Marco A. Velasco-Velázquez
  • Special Issue
  • - Volume 2017
  • - Article ID 6061729
  • - Research Article

Human Mesenchymal Stem/Stromal Cells from Umbilical Cord Blood and Placenta Exhibit Similar Capacities to Promote Expansion of Hematopoietic Progenitor Cells In Vitro

Guadalupe R. Fajardo-Orduña | Héctor Mayani | ... | Juan J. Montesinos
  • Special Issue
  • - Volume 2017
  • - Article ID 5160261
  • - Review Article

Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury

Woon Ryoung Kim | Minjin Kang | ... | Dongho Geum
  • Special Issue
  • - Volume 2017
  • - Article ID 9428176
  • - Review Article

Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models

Tai-Chi Lin | Magdalene J. Seiler | ... | Biju B. Thomas
  • Special Issue
  • - Volume 2017
  • - Article ID 7602951
  • - Review Article

Transit-Amplifying Cells in the Fast Lane from Stem Cells towards Differentiation

Emma Rangel-Huerta | Ernesto Maldonado
  • Special Issue
  • - Volume 2017
  • - Article ID 1479137
  • - Research Article

Maintenance of a Schwann-Like Phenotype in Differentiated Adipose-Derived Stem Cells Requires the Synergistic Action of Multiple Growth Factors

Alice E. Mortimer | Alessandro Faroni | ... | Adam J. Reid
  • Special Issue
  • - Volume 2017
  • - Article ID 7284872
  • - Research Article

Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGFβ Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid

Olga Gordeeva | Sergey Khaydukov
  • Special Issue
  • - Volume 2017
  • - Article ID 3027520
  • - Review Article

In Utero Stem Cell Transplantation: Potential Therapeutic Application for Muscle Diseases

Neeladri Chowdhury | Atsushi Asakura
  • Special Issue
  • - Volume 2017
  • - Article ID 6082684
  • - Research Article

hTERT-Immortalized Bone Mesenchymal Stromal Cells Expressing Rat Galanin via a Single Tetracycline-Inducible Lentivirus System

Ke An | Hui-ping Liu | ... | Zhi-heng Liu
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore7.200
Impact Factor3.869
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