The Scientific World Journal

The Scientific World Journal / 2003 / Article
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Volume 3 |Article ID 641762 |

Xiang-Dong Gao, Stefan Albert, "A Role for Exocytosis in the Spatial Regulationof Actin Organization", The Scientific World Journal, vol. 3, Article ID 641762, 4 pages, 2003.

A Role for Exocytosis in the Spatial Regulationof Actin Organization


The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role in the spatial regulation of actin organization. Our findings suggest that the actin cytoskeleton, exocytosis, and perhaps endocytosis, may depend on each other for efficiency and reinforce each other.

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