Sequence Variants of ADIPOQ and Association with Type 2 Diabetes Mellitus in Taiwan Chinese Han Population

Table 4

Genotype frequencies (%) of SNPs: T2DM and controls.

dbSNP ID	𝑛	Genotypes (%)			P value	Dominant		Recessive
						OR (95% CI)	P value	OR (95% CI)	P value
ADIPOQ		TT	TG	GG		TG + GG/TT		TT + TG/GG
rs2241766
T2DM	149	71 (47.7)	69 (46.3)	9 (6)	0.967	0.91 (−0.10~0.14)	0.684	1.49 (−0.18~0.07)	0.39
Control	139	70 (50.4)	57 (41)	12 (8.6)
ADIPOQ		GG	GT	TT		GT + TT/GG		GG + GT/TT
rs1501299
T2DM	149	80 (53.7)	53 (35.6)	16 (10.7)	0.042*	0.59 (0.01~0.24)	0.032*	0.66 (−0.07~0.2)	0.32
Control	139	92 (66.2)	37 (26.6)	10 (7.2)
TCF7L2		CC	CT	TT				CC/CT
rs7903146
T2DM	149	143 (96)	6 (4)	0 (0)	0.246			1.85 (−0.09~0.22)	0.25
Control	139	129 (92.8)	10 (7.2)	0 (0)
TCF7L2		GG	GT	GG
rs12255372
T2DM	149	149 (100)	0 (0)	0 (0)	NA
Control	139	139 (100)	0 (0)	0 (0)

∗P < 0.05; NA: nonavailable; OR: odds ratios; CI: confidence interval.