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The Scientific World Journal
Volume 2014, Article ID 937051, 8 pages
http://dx.doi.org/10.1155/2014/937051
Research Article

The Antiproliferative and Apoptotic Effects of Sirtinol, a Sirtuin Inhibitor on Human Lung Cancer Cells by Modulating Akt/β-Catenin-Foxo3A Axis

1Department of Thoracic Surgery, Chi-Mei Medical Center, Tainan 710, Taiwan
2Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan
3Department of Biological Sciences, National Sun Yat-sen University, 70 Lien Hai Road, Kaohsiung 804, Taiwan
4Department of Fragrance and Cosmetics Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan
5Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan
6Department of Biological Sciences and Technology, National University of Tainan, Tainan 700, Taiwan
7Translational Research Center, Cancer Center, Department of Medical Research, and Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan

Received 18 June 2014; Revised 29 June 2014; Accepted 30 June 2014; Published 12 August 2014

Academic Editor: Li-Yeh Chuang

Copyright © 2014 Yao Fong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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