State of the Art of Fuzzy Methods for Gene Regulatory Networks Inference

Table 3

Comparison of FIS versus other hybrid methods.

Characteristics	Methods
	FIS	AFEGRN	CGRN	Fuzzy clustering and BNs	FCMs
Automatic model parameters estimation, for example, number of clusters for fuzzy -means	No	Yes
Cross platform GRNs fusion	No		Yes
Eliminate the experimental and platform bias	No		Yes
Reduction of search space/complexity	No	No		Yes (better than traditional BNs)	Yes (better than BNs and ODEs)

NT means “not tested” (information not available): the corresponding method has not been tested against the specific characteristic mentioned in Table 3.