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World AIDS DAY: Survival, Quality of Life, and Coinfection

Authors | Science | Researchers
Person holding red ribbon to symbolise World AIDS day

This World AIDS Day, we spotlight three recent articles, covering survival post-HAART, the impact of HIV disclosure on quality of life, and modeling the dynamics of HIV-Hepatitis B coinfection. These articles reveal a comprehensive approach to HIV/AIDS research beyond medical treatments and urge for global awareness and progress.


World AIDS Day is a significant reminder of the ongoing global effort to combat HIV and AIDS. To mark the day, we’re showcasing three recent noteworthy articles that shed light on the current landscape of HIV/AIDS and pave the way for innovative treatments, public health strategies, and prevention efforts. Take a look at some research key findings and read the full articles below. 

"Factors Influencing Survival Status of HIV/AIDS after HAART in Huzhou City, Eastern China” 

Meihua Jin, et al 

Published in the Canadian Journal of Infectious Diseases and Medical Microbiology, this study takes a closer look at the survival status of HIV/AIDS patients post highly active antiretroviral therapy (HAART). Researchers analyzed data encompassing sociodemographic characteristics, treatment information, and follow-up results. 

Key findings: 

  • Elderly respondents, those with heterosexual transmission, and individuals in advanced clinical stages (stage III or IV) were more likely to have died. 

  • Those with a baseline CD4+ T-lymphocyte count of 200 cells/μL or more exhibited a higher likelihood of survival.  

  • Initiating HAART in the early clinical stages is greatly important.  

  • Health services for HIV/AIDS patients after taking medication must be strengthened to encourage patients to stick to therapeutic regimens and improve their quality of life. 

Read the full article on AIDS/HIV survival and HAART>> 

"HIV Status Disclosure and Quality of Life of People Living with HIV/AIDS" 

Adams Agbeko, Volta Regional Health Directorate, Ho, Ghana, et al. 

This study published in Advances in Public Health, explores the complex interplay between HIV status disclosure and quality of life. By examining 311 people living with HIV (PLWHIV), this research emphasises the need for tailored interventions that consider the relationship between HIV status disclosure, treatment duration, and overall quality of life. 

Key findings:  

  • 88.7% of participants disclosed their HIV status, with a majority (98.1%) reporting good quality of life.  

  • Patients on antiretroviral therapy (ART) for an extended period were significantly more likely to disclose their HIV status.  

  • Increasing years on ART, being employed, and higher educational levels predicted good quality of life in social and physical domains. 

  • The disclosure of HIV seropositive status did not correlate with quality of life. 

Read the full article on HIV/AIDS disclosure and quality of life>> 

"Modeling the Effect of Vaccination and Treatment on the Transmission Dynamics of Hepatitis B Virus and HIV/AIDS Coinfection" 

Engida Endriyas Endashaw and Temesgen Tibebu Mekonnen 

This mathematical modeling study published in the Journal of Applied Mathematics, introduces a novel perspective on coinfection dynamics. Researchers focused on individuals with coinfection of HIV and hepatitis B virus (HBV), a population more susceptible to severe health complications.  

Key findings: 

  • A deterministic mathematical model is proposed to explore the impact of vaccination against HBV and treatment for all infections on the transmission dynamics of HBV-HIV/AIDS coinfection in a population. 

  • Sensitivity analysis illustrated the influence of different parameters on the effective reproduction number of HBV-HIV/AIDS coinfection model, identifying the most sensitive parameters as wB and wH, which are the effective contact rates for HBV and HIV transmission, respectively. 

  • When the vaccination and treatment rates are increased, the number of individuals susceptible to both infections and HBV-HIV/AIDS coinfection decreases and even falls to zero over time. 

 Read the full article on HIV/AIDS and Hepatitis B coinfection>> 


These studies demonstrate how AIDS research encompasses and extends beyond medical treatments. It involves understanding social dynamics, improving healthcare delivery, and understanding how different factors affect the well-being and survival of individuals with HIV/AIDS. 

This World AIDS Day, let's spread awareness and advocate for progress, moving us closer to a world free from the challenges of HIV and AIDS. 


This blog post is distributed under the Creative Commons Attribution License (CC-BY). Illustration by David Jury.

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