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Advances in Materials Science and Engineering
Volume 2013 (2013), Article ID 380716, 12 pages
Research Article

Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide

1Technical University of Cluj-Napoca, Muncii Avenue 103-105, 400641 Cluj-Napoca, Romania
2National Institute for Research and Development of Isotopic and Molecular Technologies, Donath Street 65-103, 400293 Cluj-Napoca, Romania
3National Institute for Research and Development in Microtechnologies, Erou Iancu Nicolae Street 126 A, 077190 Bucharest, Romania
4Babeş-Bolyai University, “Raluca Ripan” Institute for Research in Chemistry, Fântânele Street 30, 400294 Cluj-Napoca, Romania

Received 25 May 2013; Accepted 26 September 2013

Academic Editor: Weihua Tang

Copyright © 2013 Violeta Paşcalău et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aim of this paper is obtaining and characterizing hydrogels based on different ratios of oxidized alginate (oA) and k-carrageenan (C), chemically cross-linked with adipic dihydrazide (adh). The alginate (A) was first oxidized with sodium metaperiodate in order to transform it into the dialdehyde derivative, a more reactive compound than alginate. A known procedure for oxidation of alginate with sodium metaperiodate in ethanol-water in order to improve alginate reactivity by transforming the hydroxyl end-groups into dialdehyde was used, preceded by a partially cleavage of the alginate chains. In the second stage, the mixture of dialdehydic derivative of oxidized alginate, k-carrageenan and glycerol subjected to reaction with adipic dihydrazide leads to a Semi-Interpenetrated Network covalently cross-linked alginate/k-carrageenan hydrogel (oACadh), based on the dihydrazone compound which is responsible for the chemical cross-linking. Pure alginate, k-carrageenan, oxidized alginate, adipic dihydrazide and the cross-linked hydrogel were characterized by: FTIR, XRD, and SEM.