The Application of Hyaluronic Acid-Based Hydrogels in Bone and Cartilage Tissue Engineering

Table 1

Binding to fibrin.

Modification	Conformation	Biochemical function/applications	References
MA	Fibrin/HA-MA hydrogel	Increased mechanical strength, BMSC proliferation, and chondrogenic potential in vitro	[98]
EDC, ADH, AHA	Fibrin/HA-AC hydrogel	DNA delivery	[58]
PCL/PLGA	PCL/PLGA stent coated with a mixture of fibrin and HA	Used as a carrier for the delivery of BMP-2 and ASCs, resulting in better bone formation and mineralization	[99]
PGA	Fibrin-stabilized 3D PGA-HA scaffold	Cultures meniscus cells, promotes the re-expression of meniscus-specific markers, and forms meniscus matrix components	[65]